Zelboraf and Calcium drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Zelboraf (vemurafenib) and Calcium (calcium). Common drug interactions include fatigue among females and affect lability among males.
The phase IV clinical study analyzes what interactions people have when they take Zelboraf and Calcium. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.
What is Zelboraf?
Zelboraf has active ingredients of vemurafenib. eHealthMe is studying from 8,392 Zelboraf users. Check the latest studies of Zelboraf.
What is Calcium?
Calcium has active ingredients of calcium. It is often used in osteoporosis. eHealthMe is studying from 184,203 Calcium users. Check the latest studies of Calcium.
24 people who take Zelboraf and Calcium together, and have interactions are studied.

What are the common drug interactions of Zelboraf and Calcium, by gender? *:
female:
- Fatigue (feeling of tiredness)
- Nausea (feeling of having an urge to vomit)
- Headache (pain in head)
- Diarrhoea
- Hypertension (high blood pressure)
- Sunburn
- Throat irritation
- Weight decreased
- Alopecia (absence of hair from areas of the body)
- Cataract (clouding of the lens inside the eye)
male:
- Affect lability (emotional incontinence)
- Anxiety
- Lymphocyte count decreased
- White blood cell count increased
- Colitis (inflammation of colon)
- Confusional state
- Decreased appetite
- Hallucination (an experience involving the perception of something not present)
- Memory impairment
- Neoplasm (tumour)
What are the common drug interactions of Zelboraf and Calcium, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Nausea (feeling of having an urge to vomit)
- Blood creatinine increased
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Electrocardiogram qrs complex prolonged
- Headache (pain in head)
- Hungry bone syndrome (hungry bone syndrome is severe low blood calcium)
- Hypocalcaemia (levels of calcium in blood serum are abnormally low)
- Loss of consciousness
- Muscle rigidity (muscle stiffness)
- Muscle spasms (muscle contraction)
50-59:
- Alopecia (absence of hair from areas of the body)
- Anaemia (lack of blood)
- Ear discomfort
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Hypertension (high blood pressure)
- Hypotension (abnormally low blood pressure)
- Nasopharyngitis (inflammation of the nasopharynx)
- Sinusitis (inflammation of sinus)
- Sleep disorder
60+:
- Nausea (feeling of having an urge to vomit)
- Fatigue (feeling of tiredness)
- Retinal haemorrhage (bleeding from retina)
- Stress
- Weight decreased
- Aphthous ulcer (mouth ulcer)
- Blood potassium decreased
- Gastric haemorrhage (bleeding stomach)
- Haematemesis (vomiting of blood)
- Hepatic cyst
What are the existing conditions these people have? *
- Malignant Melanoma (skin cancer rises from melancytes): 9 people, 37.50%
- Thyroid Cancer: 4 people, 16.67%
- Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 4 people, 16.67%
- Histiocytosis (a blood disease characterized by an abnormal multiplication of macrophages): 4 people, 16.67%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 12.50%
- Erdheim-Chester Disease (abnormal multiplication of a specific type of white blood cells): 3 people, 12.50%
- Uveitis (inflammation of the uvea): 2 people, 8.33%
- Thrombocytopenia (decrease of platelets in blood): 2 people, 8.33%
- Sunburn: 2 people, 8.33%
- Irritable Bowel Syndrome: 2 people, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Zelboraf and Calcium?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Zelboraf and Calcium:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Zelboraf:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Calcium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zelboraf and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Calcium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on vemurafenib and calcium (the active ingredients of Zelboraf and Calcium, respectively), and Zelboraf and Calcium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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