Zelnorm and Avelox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zelnorm (tegaserod maleate) and Avelox (moxifloxacin hydrochloride). Common drug interactions include constipation among females and atelectasis among males.

The phase IV clinical study analyzes what interactions people have when they take Zelnorm and Avelox. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Zelnorm?

Zelnorm has active ingredients of tegaserod maleate. eHealthMe is studying from 7,261 Zelnorm users. Check the latest studies of Zelnorm.

What is Avelox?

Avelox has active ingredients of moxifloxacin hydrochloride. It is often used in sinusitis. eHealthMe is studying from 28,651 Avelox users. Check the latest studies of Avelox.



On Jul, 16, 2026

21 people who take Zelnorm and Avelox together, and have interactions are studied.

Zelnorm and Avelox drug interactions.

What are the common drug interactions of Zelnorm and Avelox, by gender? *:

female:

  1. Constipation
  2. Dysphagia (a condition in which swallowing is difficult or painful)
  3. Fatigue (feeling of tiredness)
  4. Feeling cold
  5. Headache (pain in head)
  6. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  7. Hot flush (sudden feelings of heat)
  8. Hyperlipidaemia (presence of excess lipids in the blood)
  9. Insomnia (sleeplessness)
  10. Loss of consciousness

male:

  1. Atelectasis (partial or complete collapse of the lung)
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Arteriosclerosis (thickening and hardening of arteries)
  4. Arthralgia (joint pain)
  5. Ataxia (loss of full control of bodily movements)
  6. Back pain
  7. Balanitis candida (inflammation of the glands penis by infection with candida albicans)
  8. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  9. Cerebellar infarction (impaired blood circulation to cerebellum)
  10. Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)

What are the common drug interactions of Zelnorm and Avelox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anaphylactic reaction (serious allergic reaction)
  2. Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
  3. Dyspnoea (difficult or laboured respiration)
  4. Hypertension (high blood pressure)
  5. Lip swelling
  6. Oedema peripheral (superficial swelling)
  7. Rash
  8. Respiratory distress (difficulty in breathing)

30-39:

n/a

40-49:

  1. Depression
  2. Aortic valve prolapse
  3. Back pain
  4. Cardiac disorder
  5. Cardiac failure congestive
  6. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  7. Endocarditis (inflammation in heart muscle)
  8. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  9. Mitral valve prolapse (heart's mitral valve doesn't work well)
  10. Thyroid disorder (thyroid diseases)

50-59:

  1. Dysarthria (speech disorder)
  2. Dyspepsia (indigestion)
  3. Dysphagia (a condition in which swallowing is difficult or painful)
  4. Dyspnoea (difficult or laboured respiration)
  5. Headache (pain in head)
  6. Hyperlipidaemia (presence of excess lipids in the blood)
  7. Irritable bowel syndrome
  8. Loss of consciousness
  9. Myalgia (muscle pain)
  10. Nausea (feeling of having an urge to vomit)

60+:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Acute respiratory failure
  4. Akathisia (a movement disorder characterized by a feeling of inner restlessness)
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  6. Ascites (accumulation of fluid in the abdominal cavity)
  7. Asthenia (weakness)
  8. Balance disorder
  9. Blindness
  10. Bradycardia (abnormally slow heart action)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 28.57%
  2. Depression: 4 people, 19.05%
  3. Nausea (feeling of having an urge to vomit): 4 people, 19.05%
  4. Pain: 3 people, 14.29%
  5. Stress And Anxiety: 2 people, 9.52%
  6. Infection: 2 people, 9.52%
  7. Cardiac Disorder: 2 people, 9.52%
  8. Cough: 2 people, 9.52%
  9. High Blood Cholesterol: 2 people, 9.52%
  10. Itching: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Zelnorm and Avelox?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zelnorm and Avelox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zelnorm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Avelox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zelnorm and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Avelox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tegaserod maleate and moxifloxacin hydrochloride (the active ingredients of Zelnorm and Avelox, respectively), and Zelnorm and Avelox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: