Zelnorm and Clopidogrel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zelnorm (tegaserod maleate) and Clopidogrel (clopidogrel). Common drug interactions include injury among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Zelnorm and Clopidogrel. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Zelnorm?

Zelnorm has active ingredients of tegaserod maleate. eHealthMe is studying from 7,261 Zelnorm users. Check the latest studies of Zelnorm.

What is Clopidogrel?

Clopidogrel has active ingredients of clopidogrel. It is often used in blood clots. eHealthMe is studying from 92,160 Clopidogrel users. Check the latest studies of Clopidogrel.



On Aug, 11, 2026

11 people who take Zelnorm and Clopidogrel together, and have interactions are studied.

Zelnorm and Clopidogrel drug interactions.

What are the common drug interactions of Zelnorm and Clopidogrel, by gender? *:

female:

  1. Injury
  2. Neck pain
  3. Nephritis (inflammation of the nephrons in the kidneys)
  4. Oedema (fluid collection in tissue)
  5. Pulmonary hypertension (increase in blood pressure in the lung artery)
  6. Stent placement
  7. Tricuspid valve incompetence (inefficient heart valve)
  8. Ventricular extrasystoles (premature cardiac contraction)
  9. Chronic kidney disease
  10. Renal failure (kidney dysfunction)

male:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Abdominal distension
  4. Abdominal pain
  5. Acute myocardial infarction (acute heart attack)
  6. Adenoma benign (non-cancerous tumour -secreting)
  7. Asthma
  8. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  9. Back pain
  10. Benign prostatic hyperplasia (benign enlargement of the prostate)

What are the common drug interactions of Zelnorm and Clopidogrel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal failure (kidney dysfunction)
  4. Chest pain
  5. Colonic polyp (extra part of colon tissue grow in intestine)
  6. Constipation
  7. Dizziness
  8. Dyspnoea (difficult or laboured respiration)
  9. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  10. Injury

60+:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  4. Nephritis (inflammation of the nephrons in the kidneys)
  5. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  6. Renal injury (kidney injury)
  7. Anxiety
  8. Depression
  9. Polyp
  10. Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 63.64%
  2. High Blood Cholesterol: 5 people, 45.45%
  3. Pain: 5 people, 45.45%
  4. Cardiac Disorder: 4 people, 36.36%
  5. High Blood Pressure: 4 people, 36.36%
  6. Type 2 Diabetes: 3 people, 27.27%
  7. Blood Pressure Abnormal: 3 people, 27.27%
  8. Depression: 2 people, 18.18%
  9. Nausea (feeling of having an urge to vomit): 2 people, 18.18%
  10. Neuralgia (pain in one or more nerves): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Zelnorm and Clopidogrel?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zelnorm and Clopidogrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zelnorm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Clopidogrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zelnorm and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clopidogrel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on tegaserod maleate and clopidogrel (the active ingredients of Zelnorm and Clopidogrel, respectively), and Zelnorm and Clopidogrel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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