Zemplar and Repaglinide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zemplar (paricalcitol) and Repaglinide (repaglinide). Common drug interactions include anaemia among females and arteriosclerosis among males.

The phase IV clinical study analyzes what interactions people have when they take Zemplar and Repaglinide. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Zemplar?

Zemplar has active ingredients of paricalcitol. It is often used in kidney disease. eHealthMe is studying from 15,494 Zemplar users. Check the latest studies of Zemplar.

What is Repaglinide?

Repaglinide has active ingredients of repaglinide. It is often used in diabetes. eHealthMe is studying from 8,226 Repaglinide users. Check the latest studies of Repaglinide.



On Jul, 21, 2026

15 people who take Zemplar and Repaglinide together, and have interactions are studied.

Zemplar and Repaglinide drug interactions.

What are the common drug interactions of Zemplar and Repaglinide, by gender? *:

female:

  1. Anaemia (lack of blood)
  2. Cardiac failure congestive
  3. Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
  4. Diarrhoea
  5. Hypotension (abnormally low blood pressure)
  6. Pneumonia
  7. Renal failure chronic (long lasting kidney dysfunction)
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
  10. Tachycardia (a heart rate that exceeds the range of 100 beats/min)

male:

  1. Arteriosclerosis (thickening and hardening of arteries)
  2. Cardiac arrest
  3. Fall
  4. Haemorrhage intracranial (bleeding within the skull)
  5. Quadriplegia (a four limb paralysis)
  6. Cardiac failure
  7. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  8. Cardiac enzymes increased
  9. Chronic kidney disease
  10. Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Zemplar and Repaglinide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Graft loss (graft failure)
  2. Pneumonia
  3. Transplant rejection (a transplant material is not worked)

50-59:

  1. Apnoea (suspension of external breathing)
  2. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  3. Fall
  4. Haemorrhage intracranial (bleeding within the skull)
  5. Quadriplegia (a four limb paralysis)

60+:

  1. Arteriosclerosis (thickening and hardening of arteries)
  2. Cardiac arrest
  3. Chest pain
  4. Diarrhoea
  5. Hypotension (abnormally low blood pressure)
  6. Pneumonia
  7. Renal failure (kidney dysfunction)
  8. Renal failure chronic (long lasting kidney dysfunction)
  9. Sepsis (a severe blood infection that can lead to organ failure and death)
  10. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)

What are the existing conditions these people have? *

  1. Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium): 4 people, 26.67%
  2. High Blood Cholesterol: 4 people, 26.67%
  3. High Blood Pressure: 4 people, 26.67%
  4. Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 3 people, 20.00%
  5. Blood Glucose Increased: 3 people, 20.00%
  6. Cough: 3 people, 20.00%
  7. Eye Infection: 3 people, 20.00%
  8. Gastritis (inflammation of stomach): 3 people, 20.00%
  9. Itching: 3 people, 20.00%
  10. Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 3 people, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Zemplar and Repaglinide?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zemplar and Repaglinide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zemplar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Repaglinide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zemplar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Repaglinide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on paricalcitol and repaglinide (the active ingredients of Zemplar and Repaglinide, respectively), and Zemplar and Repaglinide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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