Zerbaxa and Paracetamol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zerbaxa (ceftolozane sulfate; tazobactam sodium) and Paracetamol (acetaminophen). Common drug interactions include haemorrhagic stroke among females and pancytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Zerbaxa and Paracetamol. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Zerbaxa?

Zerbaxa has active ingredients of ceftolozane sulfate; tazobactam sodium. eHealthMe is studying from 1,018 Zerbaxa users. Check the latest studies of Zerbaxa.

What is Paracetamol?

Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 115,650 Paracetamol users. Check the latest studies of Paracetamol.



On Jul, 05, 2026

39 people who take Zerbaxa and Paracetamol together, and have interactions are studied.

Zerbaxa and Paracetamol drug interactions.

What are the common drug interactions of Zerbaxa and Paracetamol, by gender? *:

female:

  1. Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)

male:

  1. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  2. Confusional state
  3. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  4. Hepatocellular injury (liver injury)
  5. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  6. Hypokalaemia (low potassium)
  7. Marrow hyperplasia (increased bone marrow)
  8. Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed)
  9. Roseolovirus test positive

What are the common drug interactions of Zerbaxa and Paracetamol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  2. Confusional state
  3. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  4. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  5. Marrow hyperplasia (increased bone marrow)
  6. Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed)
  7. Roseolovirus test positive

50-59:

n/a

60+:

  1. Hepatocellular injury (liver injury)
  2. Hypokalaemia (low potassium)
  3. Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)

What are the existing conditions these people have? *

  1. High Blood Pressure: 28 people, 71.79%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 28 people, 71.79%
  3. Fungal Infection: 28 people, 71.79%
  4. Diarrhea: 28 people, 71.79%
  5. Cellulitis (infection under the skin): 28 people, 71.79%
  6. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 25 people, 64.10%
  7. Fever: 16 people, 41.03%
  8. Abdominal Pain: 16 people, 41.03%
  9. Staphylococcal Bacteraemia (a bacterial infection of blood): 7 people, 17.95%
  10. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 7 people, 17.95%

* Approximation only. Some reports may have incomplete information.

Do you take Zerbaxa and Paracetamol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zerbaxa and Paracetamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zerbaxa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Paracetamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zerbaxa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Paracetamol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ceftolozane sulfate; tazobactam sodium and acetaminophen (the active ingredients of Zerbaxa and Paracetamol, respectively), and Zerbaxa and Paracetamol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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