Zestoretic and Q10 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zestoretic (hydrochlorothiazide; lisinopril) and Q10 (coenzyme q - 10). Common drug interactions include arthralgia among females and sleep apnoea syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Zestoretic and Q10. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Zestoretic?

Zestoretic has active ingredients of hydrochlorothiazide; lisinopril. It is often used in high blood pressure. eHealthMe is studying from 4,342 Zestoretic users. Check the latest studies of Zestoretic.

What is Q10?

Q10 has active ingredients of coenzyme q - 10. eHealthMe is studying from 34,259 Q10 users. Check the latest studies of Q10.

On Jul, 17, 2026

18 people who take Zestoretic and Q10 together, and have interactions are studied.

What are the common drug interactions of Zestoretic and Q10, by gender? *:

female:

Arthralgia (joint pain)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Breast cancer
Skin disorder (skin disease)
Adenoma benign (non-cancerous tumour -secreting)
Amylase increased
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthropathy
Back pain

male:

Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Asthenia (weakness)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Cerebral haemorrhage (bleeding within the brain)
Fatigue (feeling of tiredness)
Haematemesis (vomiting of blood)
Melaena (the passage of black, tarry stools)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Myalgia (muscle pain)
Onychomycosis (fungal infection of the nail)

What are the common drug interactions of Zestoretic and Q10, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Back pain
Bone pain
Breast cancer
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Colitis (inflammation of colon)
Diarrhoea
Emotional distress
Fatigue (feeling of tiredness)

60+:

Arthralgia (joint pain)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Cerebral haemorrhage (bleeding within the brain)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dizziness
Fibrocystic breast disease (a condition causing breast pain, cysts, and noncancerous breast lumps, affects many women)
Haematemesis (vomiting of blood)
Haemorrhagic anaemia (anaemia due to excessive bleeding)
Hypercoagulation (increased tendency for clotting of the blood)
Hyperlipidaemia (presence of excess lipids in the blood)

What are the existing conditions these people have? *

Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 4 people, 22.22%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 16.67%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 11.11%
Multiple Myeloma (cancer of the plasma cells): 2 people, 11.11%
Type 2 Diabetes: 1 person, 5.56%
Lipids Abnormal: 1 person, 5.56%
High Blood Cholesterol: 1 person, 5.56%
Breast Cancer: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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