Zestoretic and Ventolin hfa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zestoretic (hydrochlorothiazide; lisinopril) and Ventolin hfa (albuterol sulfate). Common drug interactions include depression among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Zestoretic and Ventolin hfa. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Zestoretic?

Zestoretic has active ingredients of hydrochlorothiazide; lisinopril. It is often used in high blood pressure. eHealthMe is studying from 4,342 Zestoretic users. Check the latest studies of Zestoretic.

What is Ventolin hfa?

Ventolin hfa has active ingredients of albuterol sulfate. It is often used in asthma. eHealthMe is studying from 40,061 Ventolin hfa users. Check the latest studies of Ventolin hfa.

On Jul, 06, 2026

23 people who take Zestoretic and Ventolin hfa together, and have interactions are studied.

Zestoretic and Ventolin hfa drug interactions.

What are the common drug interactions of Zestoretic and Ventolin Hfa, by gender? *:

female:

Depression
Nausea (feeling of having an urge to vomit)
Abdominal pain upper
Asthenia (weakness)
Back pain
Chronic kidney disease
Fatigue (feeling of tiredness)
Malaise (a feeling of general discomfort or uneasiness)
Nasopharyngitis (inflammation of the nasopharynx)
Pain

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Lip dry
Osteopenia (a condition where bone mineral density is lower than normal)
Chronic kidney disease
Depression
Emotional distress
Mobility decreased (ability to move is reduced)
Pain
Anaphylactic reaction (serious allergic reaction)

What are the common drug interactions of Zestoretic and Ventolin Hfa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Fatigue (feeling of tiredness)
Abdominal pain upper
Asthenia (weakness)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Decreased appetite
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dehydration (dryness resulting from the removal of water)
Depression
Headache (pain in head)
Metrorrhagia (uterine bleeding at irregular intervals)

50-59:

Cardiac arrest
Cardiac disorder
Cardiomyopathy (weakening of the heart muscle)
Intervertebral disc operation
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pulmonary embolism (blockage of the main artery of the lung)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Respiratory distress (difficulty in breathing)
Abasia (inability to walk)
Abdominal abscess (collection of pus in abdomen)

60+:

Chronic kidney disease
Depression
Dysphonia (speech disorder attributable to a disorder of phonation)
Feeling jittery
Gait disturbance
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypoaesthesia (reduced sense of touch or sensation)
Lip dry
Malaise (a feeling of general discomfort or uneasiness)
Nasopharyngitis (inflammation of the nasopharynx)

What are the existing conditions these people have? *

Pain: 8 people, 34.78%
Wheezing (a high-pitched whistling sound made while you breath): 5 people, 21.74%
Stress And Anxiety: 3 people, 13.04%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 13.04%
Type 2 Diabetes: 2 people, 8.70%
Muscle Spasms (muscle contraction): 2 people, 8.70%
Hiv Infection: 2 people, 8.70%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.70%
Dyspnea (difficult or laboured breathing): 2 people, 8.70%
Depression: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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