Ziac and Avelox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ziac (bisoprolol fumarate; hydrochlorothiazide) and Avelox (moxifloxacin hydrochloride). Common drug interactions include pleuritic pain among females and acute myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Ziac and Avelox. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Ziac?

Ziac has active ingredients of bisoprolol fumarate; hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 4,451 Ziac users. Check the latest studies of Ziac.

What is Avelox?

Avelox has active ingredients of moxifloxacin hydrochloride. It is often used in sinusitis. eHealthMe is studying from 28,651 Avelox users. Check the latest studies of Avelox.

On Jul, 27, 2026

35 people who take Ziac and Avelox together, and have interactions are studied.

What are the common drug interactions of Ziac and Avelox, by gender? *:

female:

Pleuritic pain
Productive cough
Pulmonary embolism (blockage of the main artery of the lung)
Renal cancer (cancer of kidney)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Renal injury (kidney injury)
Respiratory tract congestion (blockage on respiratory system)
Rhinitis allergic (inflammation of the nasal airways due to allergy)
Rhinorrhoea (watery mucus discharge from the nose)

male:

Acute myocardial infarction (acute heart attack)
Asthenia (weakness)
Nervousness
Otitis media (inflammation of the middle ear)
Pain
Pain in extremity
Swelling
Angina pectoris (chest pain due to ischemia of the heart muscle)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Bone pain

What are the common drug interactions of Ziac and Avelox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Back pain
Chest pain
Cough
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Exercise tolerance decreased
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Pleuritic pain
Pulmonary embolism (blockage of the main artery of the lung)

40-49:

Acute myocardial infarction (acute heart attack)
Asthenia (weakness)
Blood cholesterol increased
Cardiac failure congestive
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Depression
Dizziness
Emotional distress
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Nasopharyngitis (inflammation of the nasopharynx)

50-59:

Contusion (a type of hematoma of tissue in which capillaries)
Haemorrhagic diathesis (bleeding tendency)
Hypersensitivity
Platelet count decreased
Breast cancer
Chronic kidney disease
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Cough
Injury
Mouth haemorrhage (bleeding from mouth)

60+:

Chronic kidney disease
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Vertigo
Dehydration (dryness resulting from the removal of water)
Dyspepsia (indigestion)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Renal injury (kidney injury)
Diarrhoea

What are the existing conditions these people have? *

Arthritis (form of joint disorder that involves inflammation of one or more joints): 16 people, 45.71%
Depression: 14 people, 40.00%
Sleep Disorder: 13 people, 37.14%
Nausea (feeling of having an urge to vomit): 13 people, 37.14%
Muscle Spasms (muscle contraction): 13 people, 37.14%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 13 people, 37.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 17.14%
Pain: 4 people, 11.43%
Pneumonia: 3 people, 8.57%
Infection: 3 people, 8.57%

* Approximation only. Some reports may have incomplete information.

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