Zinacef and Prednisolone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zinacef (cefuroxime sodium) and Prednisolone (prednisolone). Common drug interactions include pain among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Zinacef and Prednisolone. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Zinacef?

Zinacef has active ingredients of cefuroxime sodium. eHealthMe is studying from 1,802 Zinacef users. Check the latest studies of Zinacef.

What is Prednisolone?

Prednisolone has active ingredients of prednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 212,675 Prednisolone users. Check the latest studies of Prednisolone.

On Jul, 09, 2026

56 people who take Zinacef and Prednisolone together, and have interactions are studied.

Zinacef and Prednisolone drug interactions.

What are the common drug interactions of Zinacef and Prednisolone, by gender? *:

female:

Pain
Pyrexia (fever)
Rash
Drug level decreased
Pneumonia
Arthralgia (joint pain)
Pulmonary embolism (blockage of the main artery of the lung)
Abdominal pain upper
Hypoaesthesia (reduced sense of touch or sensation)
Infection

male:

Diarrhoea
Pain
Blood bilirubin increased
Bone marrow failure
Cardiac arrest
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Fungus serology test positive
Gastritis haemorrhagic (inflammation of stomach with bleeding)
Hepatic failure (liver failure)
Hyperkalaemia (damage to or disease of the kidney)

What are the common drug interactions of Zinacef and Prednisolone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Blood bilirubin increased
Hepatic enzyme increased
Liver disorder (liver diseases)
Neutropenia (an abnormally low number of neutrophils)
Transaminases increased

30-39:

Death
Bone marrow failure
Hepatic failure (liver failure)
Ascites (accumulation of fluid in the abdominal cavity)
Blood albumin decreased
Encephalopathy (functioning of the brain is affected by some agent or condition)
Hepatosplenomegaly (enlargement of both the liver and the spleen)
Thrombocytopenia (decrease of platelets in blood)
Anaemia (lack of blood)
Diarrhoea

40-49:

Drug ineffective
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Drug intolerance (drug sensitivity)
Ileal ulcer
Diarrhoea
Drug level decreased
Pyrexia (fever)
Rash
Nausea (feeling of having an urge to vomit)
Pneumonia

50-59:

Fungus serology test positive
Gastritis haemorrhagic (inflammation of stomach with bleeding)
Hyperkalaemia (damage to or disease of the kidney)
Myopathy (a muscular disease in which the muscle fibres do not function)
Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon)
Dehydration (dryness resulting from the removal of water)
Dysphagia (a condition in which swallowing is difficult or painful)
Abdominal pain upper
Blood creatine phosphokinase increased
Death

60+:

Diarrhoea
Malaise (a feeling of general discomfort or uneasiness)
Bone marrow depression (decreased ability or inability of the bone marrow to produce blood cells)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Erythema (redness of the skin)
Hyperhidrosis (abnormally increased sweating)
Hypoxia (low oxygen in tissues)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Pain
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

What are the existing conditions these people have? *

Malignant Melanoma (skin cancer rises from melancytes): 12 people, 21.43%
Hiv Infection: 9 people, 16.07%
Diarrhea: 8 people, 14.29%
High Blood Cholesterol: 7 people, 12.50%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 6 people, 10.71%
Clostridium Difficile Colitis (inflammation of colon by clostridium difficile bacteria infection): 6 people, 10.71%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 5.36%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 3 people, 5.36%
Pneumonia: 3 people, 5.36%
Osteoporosis (bones weak and more likely to break): 3 people, 5.36%

* Approximation only. Some reports may have incomplete information.

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