Zithromax and Nitrofurantoin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zithromax (azithromycin) and Nitrofurantoin (nitrofurantoin, macrocrystalline). Common drug interactions include dysphonia among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Zithromax and Nitrofurantoin. It is created by eHealthMe based on reports of 95 people who take the same drugs from the FDA, and is updated regularly.

What is Zithromax?

Zithromax has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 35,525 Zithromax users. Check the latest studies of Zithromax.

What is Nitrofurantoin?

Nitrofurantoin has active ingredients of nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 4,837 Nitrofurantoin users. Check the latest studies of Nitrofurantoin.

On Jul, 15, 2026

95 people who take Zithromax and Nitrofurantoin together, and have interactions are studied.

Zithromax and Nitrofurantoin drug interactions.

What are the common drug interactions of Zithromax and Nitrofurantoin, by gender? *:

female:

Dysphonia (speech disorder attributable to a disorder of phonation)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Myalgia (muscle pain)
Osteomyelitis (infection of bone)
Cough
Dizziness
Emotional distress
Malaise (a feeling of general discomfort or uneasiness)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Oropharyngeal pain

male:

Anxiety
Dyspnoea (difficult or laboured respiration)
Tremor (trembling or shaking movements in one or more parts of your body)
Vomiting
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Anaemia (lack of blood)
Balance disorder
Cellulitis (infection under the skin)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Diabetes mellitus inadequate control

What are the common drug interactions of Zithromax and Nitrofurantoin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Scar
Anaemia (lack of blood)
Angiopathy (generic term for a disease of the blood vessels)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)
Arthropathy
Back pain
Bone disorder
Bone loss

10-19:

Abdominal distension
Abdominal pain upper
Aphagia (inability or refusal to swallow)
Biliary colic
Cholecystitis chronic (long lasting infection of gallbladder)
Cholesterosis (abnormal deposition of cholesterol in tissues)
Constipation
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Eructation (release of gas from the digestive tract)

20-29:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Anxiety
Pulmonary embolism (blockage of the main artery of the lung)
Abdominal distension
Abdominal pain
Abdominal pain upper
Abdominal tenderness
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Chest pain
Cholecystitis acute (rapid infection of gallbladder)

30-39:

Anxiety
Pain
Discomfort
Fear
Oedema peripheral (superficial swelling)
Pain in extremity
Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)
Venous injury
Venous insufficiency (poor circulation of blood caused by damaged or enlarged veins)
Anxiety disorder

40-49:

Blood cholesterol increased
Cellulitis (infection under the skin)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Ear disorder
Ear infection
Eye pain
Hyperlipidaemia (presence of excess lipids in the blood)
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Nasopharyngitis (inflammation of the nasopharynx)
Obesity (having too much body fat)

50-59:

Bone pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Dizziness
Vomiting
Abdominal pain
Abscess (pus)
Anaemia (lack of blood)
Asthma
Chills (felling of cold)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

60+:

Fall
Anxiety
Myalgia (muscle pain)
Dyspnoea (difficult or laboured respiration)
Back pain
Diarrhoea
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Cough
Oropharyngeal pain
Palpitations (feelings or sensations that your heart is pounding or racing)

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 28 people, 29.47%
Pain: 14 people, 14.74%
Birth Control: 10 people, 10.53%
Muscle Spasms (muscle contraction): 8 people, 8.42%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 6.32%
Depression: 6 people, 6.32%
Stress And Anxiety: 5 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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