Zmax and Profen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zmax (azithromycin) and Profen (ibuprofen). Common drug interactions include abdominal discomfort among females.

The phase IV clinical study analyzes what interactions people have when they take Zmax and Profen. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Zmax?

Zmax has active ingredients of azithromycin. It is often used in bronchitis. eHealthMe is studying from 317 Zmax users. Check the latest studies of Zmax.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

On Jul, 07, 2026

12 people who take Zmax and Profen together, and have interactions are studied.

What are the common drug interactions of Zmax and Profen, by gender? *:

female:

Abdominal discomfort
Abdominal pain upper
Hyperthyroidism (over activity of the thyroid gland)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Infectious mononucleosis (infection usually caused by the epstein-barr virus)
Influenza
Metastasis (spreadable cancer to other organ from origin)
Nausea (feeling of having an urge to vomit)
Nocturia (the need to get up in the night to urinate)
Obesity (having too much body fat)

male:

n/a

What are the common drug interactions of Zmax and Profen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Hyperkalaemia (damage to or disease of the kidney)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal hypertension (high blood pressure caused by the kidneys hormonal response)

40-49:

Abdominal discomfort
Abdominal pain upper
Anaemia (lack of blood)
Arthralgia (joint pain)
Carbohydrate metabolism disorder (inability of carbohydrate metabolism)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Diarrhoea
Headache (pain in head)
Herpes simplex (herpes simplex is a common viral infection)
Hyperhidrosis (abnormally increased sweating)

50-59:

Chronic kidney disease
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

60+:

Atypical femur fracture
Bone disorder
Osteoporosis (bones weak and more likely to break)
Ovarian cyst (fluid filled sac of the ovary)
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pathological fracture (broken bone caused by disease)
Pneumonia
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Tendonitis (a condition that causes pain and swelling of tendons)

What are the existing conditions these people have? *

Depression: 8 people, 66.67%
Stress And Anxiety: 7 people, 58.33%
Bipolar Disorder (mood disorder): 7 people, 58.33%
Sleep Disorder: 6 people, 50.00%
Anger: 5 people, 41.67%
High Blood Cholesterol: 2 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 16.67%
Viral Infection: 1 person, 8.33%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 8.33%
Osteoporosis (bones weak and more likely to break): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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