Zocor and Midazolam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zocor (simvastatin) and Midazolam (midazolam). Common drug interactions include dyspepsia among females and sepsis among males.

The phase IV clinical study analyzes what interactions people have when they take Zocor and Midazolam. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Zocor?

Zocor has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 86,545 Zocor users. Check the latest studies of Zocor.

What is Midazolam?

Midazolam has active ingredients of midazolam. eHealthMe is studying from 11,246 Midazolam users. Check the latest studies of Midazolam.

On Jul, 20, 2026

38 people who take Zocor and Midazolam together, and have interactions are studied.

What are the common drug interactions of Zocor and Midazolam, by gender? *:

female:

Dyspepsia (indigestion)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Pain
Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
Procedural pain
Pyrexia (fever)
Drug ineffective
Abdominal pain
Anaemia (lack of blood)

male:

Sepsis (a severe blood infection that can lead to organ failure and death)
Death
Perirectal abscess
Scrotal abscess (pus in scrotum)
Blood creatine phosphokinase increased
Constipation
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Fall
Hypotension (abnormally low blood pressure)
Impaired healing

What are the common drug interactions of Zocor and Midazolam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)

40-49:

Abscess (pus)
Anal abscess
Anxiety
Cellulitis (infection under the skin)
Chronic kidney disease
Depression
Folliculitis (infection of hair root)
Groin abscess (pus in groin)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)

50-59:

Sepsis (a severe blood infection that can lead to organ failure and death)
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Anal abscess
Cellulitis (infection under the skin)
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Perioral dermatitis (facial rash that causes bumps to develop around the mouth)
Psoriasis (immune-mediated disease that affects the skin)

60+:

Pyrexia (fever)
Dyspepsia (indigestion)
Anaemia (lack of blood)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Colitis (inflammation of colon)
Colitis ulcerative (inflammation of colon with ulcer)
Erythema (redness of the skin)
Female genital tract fistula (passage in genital tract of female)
Frequent bowel movements
Haematochezia (passage of stools containing blood)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 23.68%
High Blood Pressure: 7 people, 18.42%
Type 2 Diabetes: 7 people, 18.42%
Nausea (feeling of having an urge to vomit): 6 people, 15.79%
Allergies: 6 people, 15.79%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 15.79%
Diabetes: 6 people, 15.79%
Pain: 6 people, 15.79%
Hypotension (abnormally low blood pressure): 5 people, 13.16%
Weight Decreased: 5 people, 13.16%

* Approximation only. Some reports may have incomplete information.

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