Zofran odt and Metoclopramide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zofran odt (ondansetron) and Metoclopramide (metoclopramide hydrochloride). Common drug interactions include dehydration among females.

The phase IV clinical study analyzes what interactions people have when they take Zofran odt and Metoclopramide. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Zofran odt?

Zofran odt has active ingredients of ondansetron. It is often used in nausea. eHealthMe is studying from 2,092 Zofran odt users. Check the latest studies of Zofran odt.

What is Metoclopramide?

Metoclopramide has active ingredients of metoclopramide hydrochloride. It is often used in nausea. eHealthMe is studying from 81,263 Metoclopramide users. Check the latest studies of Metoclopramide.

On Jul, 31, 2026

13 people who take Zofran odt and Metoclopramide together, and have interactions are studied.

Zofran odt and Metoclopramide drug interactions.

What are the common drug interactions of Zofran Odt and Metoclopramide, by gender? *:

female:

Dehydration (dryness resulting from the removal of water)
Diarrhoea
Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
Anaemia (lack of blood)
Colitis (inflammation of colon)
Decreased appetite
Failure to thrive (inadequate weight gain and physical growth in children)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Pneumonia
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)

male:

n/a

What are the common drug interactions of Zofran Odt and Metoclopramide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Asthenia (weakness)
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)

30-39:

n/a

40-49:

Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Pain
Alopecia (absence of hair from areas of the body)
Ankle fracture
Anxiety
Aphasia (damage to the parts of the brain that control language)
Arthralgia (joint pain)
Balance disorder
Cellulitis (infection under the skin)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)

50-59:

n/a

60+:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Pneumonia
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Renal failure (kidney dysfunction)
Urinary tract infection

What are the existing conditions these people have? *

Diabetes: 5 people, 38.46%
Nausea And Vomiting: 5 people, 38.46%
Appetite Disorder (abnormal eating habits): 4 people, 30.77%
Oropharyngeal Pain: 4 people, 30.77%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 30.77%
Cough: 4 people, 30.77%
Pain: 4 people, 30.77%
High Blood Cholesterol: 4 people, 30.77%
Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 3 people, 23.08%
Constipation: 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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