Zofran and Tyrosine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zofran (ondansetron hydrochloride) and Tyrosine (tyrosine). Common drug interactions include blood alkaline phosphatase increased among females and abnormal dreams among males.

The phase IV clinical study analyzes what interactions people have when they take Zofran and Tyrosine. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Zofran?

Zofran has active ingredients of ondansetron hydrochloride. It is often used in nausea. eHealthMe is studying from 94,987 Zofran users. Check the latest studies of Zofran.

What is Tyrosine?

Tyrosine has active ingredients of tyrosine. It is often used in hypothyroidism. eHealthMe is studying from 830 Tyrosine users. Check the latest studies of Tyrosine.



On Jul, 18, 2026

11 people who take Zofran and Tyrosine together, and have interactions are studied.

Zofran and Tyrosine drug interactions.

What are the common drug interactions of Zofran and Tyrosine, by gender? *:

female:

  1. Blood alkaline phosphatase increased
  2. Blood creatine phosphokinase increased
  3. Diarrhoea
  4. Malignant neoplasm progression (cancer tumour came back)
  5. Plantar fasciitis (painful inflammatory process of the plantar fascia)
  6. Rash
  7. Renal failure (kidney dysfunction)
  8. Abdominal distension
  9. Anxiety
  10. Coeliac artery compression syndrome (abdominal pain related to compression of the celiac artery)

male:

  1. Abnormal dreams
  2. Activities of daily living impaired
  3. Therapeutic response unexpected
  4. Tic (a sudden, repetitive, nonrhythmic motor movement or vocalization involving discrete muscle groups)
  5. Tremor (trembling or shaking movements in one or more parts of your body)
  6. Weight decreased
  7. Anxiety
  8. Disturbance in attention
  9. Drug hypersensitivity
  10. Fibromyalgia (a long-term condition which causes pain all over the body)

What are the common drug interactions of Zofran and Tyrosine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Malaise (a feeling of general discomfort or uneasiness)

40-49:

  1. Hypertension (high blood pressure)
  2. Liver injury
  3. Platelet count increased
  4. Urticaria (rash of round, red welts on the skin that itch intensely)
  5. Abdominal distension
  6. Coeliac artery compression syndrome (abdominal pain related to compression of the celiac artery)
  7. Hepatic steatosis (fatty liver disease)

50-59:

n/a

60+:

  1. Blood alkaline phosphatase increased
  2. Blood creatine phosphokinase increased
  3. Diarrhoea
  4. Malignant neoplasm progression (cancer tumour came back)
  5. Plantar fasciitis (painful inflammatory process of the plantar fascia)
  6. Rash
  7. Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 45.45%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 36.36%
  3. Stress And Anxiety: 2 people, 18.18%
  4. Sleep Disorder: 2 people, 18.18%
  5. Ovarian Germ Cell Cancer: 2 people, 18.18%
  6. Ovarian Cancer (cancer of ovary): 2 people, 18.18%
  7. Insomnia (sleeplessness): 2 people, 18.18%
  8. Fever: 2 people, 18.18%
  9. Depression: 2 people, 18.18%
  10. Rickets (softening of bones): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Zofran and Tyrosine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zofran and Tyrosine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zofran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tyrosine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zofran and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tyrosine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ondansetron hydrochloride and tyrosine (the active ingredients of Zofran and Tyrosine, respectively), and Zofran and Tyrosine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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