Zoledronic acid and Ultram drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zoledronic acid (zoledronic acid) and Ultram (tramadol hydrochloride). Common drug interactions include arthralgia among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Zoledronic acid and Ultram. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Zoledronic acid?

Zoledronic acid has active ingredients of zoledronic acid. eHealthMe is studying from 28,485 Zoledronic acid users. Check the latest studies of Zoledronic acid.

What is Ultram?

Ultram has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 28,425 Ultram users. Check the latest studies of Ultram.

On Jul, 11, 2026

13 people who take Zoledronic acid and Ultram together, and have interactions are studied.

Zoledronic acid and Ultram drug interactions.

What are the common drug interactions of Zoledronic Acid and Ultram, by gender? *:

female:

Arthralgia (joint pain)
Balance disorder
Blood thyroid stimulating hormone increased
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Dizziness
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Inappropriate antidiuretic hormone secretion
Injection site extravasation (flow of (blood or lymph) from injection site)
Memory impairment

male:

Fatigue (feeling of tiredness)
Constipation
Dizziness
Hypoaesthesia (reduced sense of touch or sensation)
Hypotension (abnormally low blood pressure)
Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
Muscle spasms (muscle contraction)
Nausea (feeling of having an urge to vomit)
Neuropathy peripheral (surface nerve damage)
Neutropenia (an abnormally low number of neutrophils)

What are the common drug interactions of Zoledronic Acid and Ultram, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Fatigue (feeling of tiredness)
Gastric disorder (disease of stomach)
Rash generalised (rash on most of body parts)
Constipation
Headache (pain in head)
Muscle spasms (muscle contraction)
Neuropathy peripheral (surface nerve damage)
Rash
Rash pruritic (redness with itching)
Tooth fracture

60+:

Dizziness
Arthralgia (joint pain)
Inappropriate antidiuretic hormone secretion
Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
Injection site extravasation (flow of (blood or lymph) from injection site)
Nausea (feeling of having an urge to vomit)
Neutropenia (an abnormally low number of neutrophils)
Pain in extremity
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Poor quality sleep

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 10 people, 76.92%
Osteoporosis (bones weak and more likely to break): 2 people, 15.38%
Thrombocytopenia (decrease of platelets in blood): 1 person, 7.69%
Swelling: 1 person, 7.69%
Rickets (softening of bones): 1 person, 7.69%
Neuralgia (pain in one or more nerves): 1 person, 7.69%
Nausea (feeling of having an urge to vomit): 1 person, 7.69%
High Blood Pressure: 1 person, 7.69%
Dyspnea (difficult or laboured breathing): 1 person, 7.69%
Diarrhea: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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