Zoledronic and Halaven drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zoledronic (zoledronic acid) and Halaven (eribulin mesylate). Common drug interactions include coagulopathy among females.

The phase IV clinical study analyzes what interactions people have when they take Zoledronic and Halaven. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Zoledronic?

Zoledronic has active ingredients of zoledronic acid. eHealthMe is studying from 29,812 Zoledronic users. Check the latest studies of Zoledronic.

What is Halaven?

Halaven has active ingredients of eribulin mesylate. eHealthMe is studying from 3,881 Halaven users. Check the latest studies of Halaven.



On Jul, 26, 2026

41 people who take Zoledronic and Halaven together, and have interactions are studied.

Zoledronic and Halaven drug interactions.

What are the common drug interactions of Zoledronic and Halaven, by gender? *:

female:

  1. Coagulopathy (blood's ability to clot is impaired)
  2. Neuropathy peripheral (surface nerve damage)
  3. Osteonecrosis of jaw (death of bone of jaw)
  4. Pleural effusion (water on the lungs)
  5. White blood cell count decreased
  6. Alanine aminotransferase increased
  7. Alopecia (absence of hair from areas of the body)
  8. Aspartate aminotransferase increased
  9. Atypical femur fracture
  10. Cardiac failure

male:

n/a

What are the common drug interactions of Zoledronic and Halaven, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Back pain
  2. Hypoacusis (loss of hearing)
  3. Malignant neoplasm progression (cancer tumour came back)
  4. Neoplasm progression (growth of tumour)
  5. Pleural effusion (water on the lungs)
  6. Breast cancer stage iv

40-49:

  1. Neutropenia (an abnormally low number of neutrophils)
  2. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  3. White blood cell count decreased
  4. Anaemia (lack of blood)
  5. Cauda equina syndrome (affecting the bundle of nerve roots)
  6. Disease progression
  7. Leukopenia (less number of white blood cells in blood)

50-59:

  1. Alopecia (absence of hair from areas of the body)
  2. Duodenal ulcer haemorrhage (bleeding duodenal ulcer)
  3. Febrile neutropenia (fever with reduced white blood cells)
  4. Mouth ulceration (mouth ulcers)
  5. Partial seizures (seizures which affect only a part of the brain at onset)
  6. Type 1 diabetes mellitus
  7. Coagulopathy (blood's ability to clot is impaired)
  8. Neuropathy peripheral (surface nerve damage)
  9. Neutropenia (an abnormally low number of neutrophils)
  10. Osteonecrosis of jaw (death of bone of jaw)

60+:

  1. Anaemia (lack of blood)
  2. Atypical femur fracture
  3. Fall
  4. Breast cancer
  5. Febrile neutropenia (fever with reduced white blood cells)
  6. Gastrointestinal perforation (hole in the digestive tract)

What are the existing conditions these people have? *

  1. Breast Cancer: 25 people, 60.98%
  2. Gastritis (inflammation of stomach): 19 people, 46.34%
  3. Thrombosis (formation of a blood clot inside a blood vessel): 18 people, 43.90%
  4. Gastric Ulcer (stomach ulcer): 18 people, 43.90%
  5. Folliculitis (infection of hair root): 18 people, 43.90%
  6. Cholecystitis Acute (rapid infection of gallbladder): 18 people, 43.90%
  7. Blepharitis (chronic inflammation of the eyelid): 18 people, 43.90%
  8. Biliary Sepsis: 18 people, 43.90%
  9. Abdominal Pain Upper: 18 people, 43.90%
  10. Abdominal Pain: 18 people, 43.90%

* Approximation only. Some reports may have incomplete information.

Do you take Zoledronic and Halaven?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zoledronic and Halaven:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zoledronic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Halaven:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zoledronic and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Halaven and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on zoledronic acid and eribulin mesylate (the active ingredients of Zoledronic and Halaven, respectively), and Zoledronic and Halaven (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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