Zolmitriptan and Solu-medrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zolmitriptan (zolmitriptan) and Solu-medrol (methylprednisolone sodium succinate). Common drug interactions include blood pressure systolic increased among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Zolmitriptan and Solu-medrol. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Zolmitriptan?

Zolmitriptan has active ingredients of zolmitriptan. It is often used in migraine. eHealthMe is studying from 2,568 Zolmitriptan users. Check the latest studies of Zolmitriptan.

What is Solu-medrol?

Solu-medrol has active ingredients of methylprednisolone sodium succinate. It is often used in multiple sclerosis. eHealthMe is studying from 39,410 Solu-medrol users. Check the latest studies of Solu-medrol.

On Jul, 16, 2026

33 people who take Zolmitriptan and Solu-medrol together, and have interactions are studied.

Zolmitriptan and Solu-medrol drug interactions.

What are the common drug interactions of Zolmitriptan and Solu-Medrol, by gender? *:

female:

Blood pressure systolic increased
Dizziness
Dyspnoea (difficult or laboured respiration)
Heart rate increased
Ill-defined disorder
Nausea (feeling of having an urge to vomit)
Oxygen saturation decreased
Pleurisy (inflammation of the pleurae, which causes pain when breathing)
Pulmonary oedema (fluid accumulation in the lungs)
Respiratory rate increased (excess breathing rate/min)

male:

Abdominal distension
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Fatigue (feeling of tiredness)
Febrile neutropenia (fever with reduced white blood cells)
Local swelling (swelling at the site of some application of substance or injury)
Nausea (feeling of having an urge to vomit)
Pulmonary embolism (blockage of the main artery of the lung)
Weight increased

What are the common drug interactions of Zolmitriptan and Solu-Medrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Asthenia (weakness)
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Infusion related reaction
Alopecia (absence of hair from areas of the body)
Cough
Dyspepsia (indigestion)
Fatigue (feeling of tiredness)
Hypoaesthesia teeth (reduced sense of touch or sensation)
Malaise (a feeling of general discomfort or uneasiness)

50-59:

Abdominal distension
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Bradycardia (abnormally slow heart action)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dysgeusia (disorder of the sense of taste)
Fatigue (feeling of tiredness)
Febrile neutropenia (fever with reduced white blood cells)
Local swelling (swelling at the site of some application of substance or injury)
Loss of consciousness

60+:

Blood pressure increased
Blood pressure systolic increased
Pulmonary oedema (fluid accumulation in the lungs)
Respiratory rate increased (excess breathing rate/min)
Asthenia (weakness)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Headache (pain in head)
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Lung disorder (lung disease)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)

What are the existing conditions these people have? *

Idiopathic Pulmonary Fibrosis (chronic lung disease): 28 people, 84.85%
High Blood Cholesterol: 28 people, 84.85%
Interstitial Lung Disease: 27 people, 81.82%
Pain: 25 people, 75.76%
Overlap Syndrome (an autoimmune disease of connective tissue): 14 people, 42.42%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 9 people, 27.27%
Sleep Disorder: 3 people, 9.09%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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