Zoloft and Aztreonam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zoloft (sertraline hydrochloride) and Aztreonam (aztreonam). Common drug interactions include acute sinusitis among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Zoloft and Aztreonam. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,798 Zoloft users. Check the latest studies of Zoloft.

What is Aztreonam?

Aztreonam has active ingredients of aztreonam. eHealthMe is studying from 3,054 Aztreonam users. Check the latest studies of Aztreonam.



On Jul, 12, 2026

23 people who take Zoloft and Aztreonam together, and have interactions are studied.

Zoloft and Aztreonam drug interactions.

What are the common drug interactions of Zoloft and Aztreonam, by gender? *:

female:

  1. Acute sinusitis
  2. Alopecia (absence of hair from areas of the body)
  3. Anaemia (lack of blood)
  4. Arthralgia (joint pain)
  5. Blood calcium decreased
  6. Bone cyst
  7. Bone disorder
  8. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  9. Bone pain
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

male:

  1. Pyrexia (fever)
  2. Hypotension (abnormally low blood pressure)
  3. Cardiac murmur (an heart sound in valve abnormality)
  4. Dyspnoea (difficult or laboured respiration)
  5. Empyema (collection of pus in a cavity in the body)
  6. Infectious pleural effusion (infectious fluid in the lung)
  7. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Abdominal pain
  10. Abscess (pus)

What are the common drug interactions of Zoloft and Aztreonam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
  2. Hyperammonaemia

20-29:

n/a

30-39:

  1. Respiratory failure (inadequate gas exchange by the respiratory system)
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Abdominal pain
  4. Abdominal pain upper
  5. Alpha haemolytic streptococcal infection (infections with alpha-haemolytic strep bacteria are common; many strains live naturally in humans)
  6. Blood culture positive
  7. Constipation
  8. Disease progression
  9. Drug eruption (adverse drug reaction of the skin)
  10. Faecaloma (hard mass of fecal matter)

40-49:

  1. Pyrexia (fever)
  2. Abscess (pus)
  3. Acute sinusitis
  4. Alopecia (absence of hair from areas of the body)
  5. Anaemia (lack of blood)
  6. Arthralgia (joint pain)
  7. Blood calcium decreased
  8. Bone cyst
  9. Bone disorder
  10. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)

50-59:

  1. Irritable bowel syndrome
  2. Laryngitis (inflammation of the larynx)
  3. Lung disorder (lung disease)
  4. Mass
  5. Mastication disorder (disease of chewing food)
  6. Mitral valve incompetence (inefficient heart valve)
  7. Mouth haemorrhage (bleeding from mouth)
  8. Mouth ulceration (mouth ulcers)
  9. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
  10. Myalgia (muscle pain)

60+:

  1. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  2. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  3. Cardiac murmur (an heart sound in valve abnormality)
  4. Drug toxicity
  5. Dyspnoea (difficult or laboured respiration)
  6. Empyema (collection of pus in a cavity in the body)
  7. Infectious pleural effusion (infectious fluid in the lung)
  8. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  9. Renal failure (kidney dysfunction)
  10. Sepsis (a severe blood infection that can lead to organ failure and death)

What are the existing conditions these people have? *

  1. Pain: 9 people, 39.13%
  2. Nausea (feeling of having an urge to vomit): 9 people, 39.13%
  3. Insomnia (sleeplessness): 7 people, 30.43%
  4. Multiple Myeloma (cancer of the plasma cells): 4 people, 17.39%
  5. Anaemia (lack of blood): 4 people, 17.39%
  6. Diabetes: 4 people, 17.39%
  7. Nausea And Vomiting: 4 people, 17.39%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.04%
  9. Cystic Fibrosis (disease of the secretary glands): 3 people, 13.04%
  10. Dyspnea (difficult or laboured breathing): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zoloft and Aztreonam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zoloft:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aztreonam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zoloft and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aztreonam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on sertraline hydrochloride and aztreonam (the active ingredients of Zoloft and Aztreonam, respectively), and Zoloft and Aztreonam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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