Zoloft and Intelence drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Zoloft (sertraline hydrochloride) and Intelence (etravirine). Common drug interactions include chronic kidney disease among females and emotional distress among males.
The phase IV clinical study analyzes what interactions people have when they take Zoloft and Intelence. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Zoloft?
Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,798 Zoloft users. Check the latest studies of Zoloft.
What is Intelence?
Intelence has active ingredients of etravirine. It is often used in hiv infection. eHealthMe is studying from 3,797 Intelence users. Check the latest studies of Intelence.
15 people who take Zoloft and Intelence together, and have interactions are studied.

What are the common drug interactions of Zoloft and Intelence, by gender? *:
female:
- Chronic kidney disease
- Emotional distress
- Pain
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Bone density decreased
- Tooth loss
- Asthenia (weakness)
- Fibula fracture
- Osteoporosis (bones weak and more likely to break)
- Abortion spontaneous (naturally occurring miscarriage)
male:
- Emotional distress
- Pain
- Dysstasia (difficulty in standing)
- Gait disturbance
- Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Panic attack
- Proteinuria (presence of protein in the urine)
- Quality of life decreased
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
What are the common drug interactions of Zoloft and Intelence, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Gait disturbance
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Bone density decreased
- Emotional distress
- Pain
- Abortion spontaneous (naturally occurring miscarriage)
- Cardiac disorder
- Craniosynostosis (a baby is born with an abnormally shaped skull or develops one during growth)
- Developmental delay
- Failure to thrive (inadequate weight gain and physical growth in children)
40-49:
- Chronic kidney disease
- Emotional distress
- Pain
- Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
- Renal failure (kidney dysfunction)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Asthenia (weakness)
- Bone cyst
- Bone density decreased
- Cerebral haemorrhage (bleeding within the brain)
50-59:
- Bone density decreased
- Chronic kidney disease
- Asthenia (weakness)
- Mobility decreased (ability to move is reduced)
- Tooth extraction
- Emotional distress
- Fibula fracture
- Pain
- Tooth loss
- Ankle fracture
60+:
n/a
What are the existing conditions these people have? *
- Hiv Infection: 14 people, 93.33%
- Pain: 4 people, 26.67%
- Muscle Spasms (muscle contraction): 3 people, 20.00%
- Indigestion: 2 people, 13.33%
- Dyspnea (difficult or laboured breathing): 2 people, 13.33%
- High Blood Cholesterol: 2 people, 13.33%
- Neuropathy Peripheral (surface nerve damage): 2 people, 13.33%
- Skin Infection: 2 people, 13.33%
- Bacterial Infection: 1 person, 6.67%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Zoloft and Intelence?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Zoloft and Intelence:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Zoloft:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Intelence:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zoloft and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Intelence and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
- Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on sertraline hydrochloride and etravirine (the active ingredients of Zoloft and Intelence, respectively), and Zoloft and Intelence (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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