Zoloft and Mepron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zoloft (sertraline hydrochloride) and Mepron (atovaquone). Common drug interactions include dyspnoea among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Zoloft and Mepron. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,798 Zoloft users. Check the latest studies of Zoloft.

What is Mepron?

Mepron has active ingredients of atovaquone. It is often used in babesiosis. eHealthMe is studying from 2,091 Mepron users. Check the latest studies of Mepron.

On Jul, 12, 2026

41 people who take Zoloft and Mepron together, and have interactions are studied.

What are the common drug interactions of Zoloft and Mepron, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Fungal infection
Gallbladder disorder
General physical health deterioration (weak health status)
Hepatobiliary disease (diseases affect the liver and/or biliary tract)
Hepatocellular damage (liver damage)
Hepatotoxicity (chemical-driven liver damage)
Hospitalisation
Hyperthyroidism (over activity of the thyroid gland)

male:

Diarrhoea
Vomiting
Malaise (a feeling of general discomfort or uneasiness)
Pyrexia (fever)
Rash
Sepsis (a severe blood infection that can lead to organ failure and death)
Cellulitis (infection under the skin)
Death
Dehydration (dryness resulting from the removal of water)
Eosinophilia (eosinophil count in the peripheral blood exceeds)

What are the common drug interactions of Zoloft and Mepron, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Brain neoplasm malignant (brain cancer tumour)
Neoplasm recurrence (reoccurrence of tumour)

20-29:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Back pain
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Emotional distress
Fungal infection
Gallbladder disorder
General physical health deterioration (weak health status)

30-39:

Bacterial infection
Blood lactic acid increased
Diarrhoea
Hepatocellular damage (liver damage)
Hepatotoxicity (chemical-driven liver damage)
Hyperthyroidism (over activity of the thyroid gland)
Hypokalaemia (low potassium)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Multi-organ failure (multisystem organ failure)
Nausea (feeling of having an urge to vomit)

40-49:

Biliary tract disorder
Bone cyst
Bone density decreased
Cerebral haemorrhage (bleeding within the brain)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Chronic kidney disease
Emotional distress
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Mobility decreased (ability to move is reduced)
Nausea (feeling of having an urge to vomit)

50-59:

Rash
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)
Neutropenia (an abnormally low number of neutrophils)
Pyrexia (fever)
Sinusitis (inflammation of sinus)
Thrombotic thrombocytopenic purpura (a rare blood disorder characterized by clotting in small blood vessels of the body)
Abdominal pain

60+:

Back pain
Cellulitis (infection under the skin)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Bacterial infection
Cardiac arrest
Colitis (inflammation of colon)
Confusional state
Death
Delirium (wild excitement)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)

What are the existing conditions these people have? *

Pain: 7 people, 17.07%
Nausea (feeling of having an urge to vomit): 6 people, 14.63%
Sleep Apnea Syndrome: 4 people, 9.76%
Nausea And Vomiting: 4 people, 9.76%
Multiple Myeloma (cancer of the plasma cells): 4 people, 9.76%
Hiv Infection: 4 people, 9.76%
Fever: 4 people, 9.76%
High Blood Cholesterol: 3 people, 7.32%
Diarrhea: 3 people, 7.32%
Constipation: 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

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