Zoloft and Novalgin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zoloft (sertraline hydrochloride) and Novalgin (metamizole). Common drug interactions include rash among females and infection among males.

The phase IV clinical study analyzes what interactions people have when they take Zoloft and Novalgin. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,798 Zoloft users. Check the latest studies of Zoloft.

What is Novalgin?

Novalgin has active ingredients of metamizole. It is often used in pain. eHealthMe is studying from 10,177 Novalgin users. Check the latest studies of Novalgin.

On Jul, 29, 2026

20 people who take Zoloft and Novalgin together, and have interactions are studied.

What are the common drug interactions of Zoloft and Novalgin, by gender? *:

female:

Rash
Asthenia (weakness)
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Febrile neutropenia (fever with reduced white blood cells)
Petechiae (a small red or purple spot caused by bleeding into the skin)
Pneumonia
Vasculitis (inflammation of a blood vessel or blood vessels)
Feeling of despair
Suicidal ideation

male:

Infection
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Erythema (redness of the skin)
General physical health deterioration (weak health status)
Pyrexia (fever)
Scab (a hard coating on the skin formed during the wound healing)

What are the common drug interactions of Zoloft and Novalgin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Erythema (redness of the skin)
General physical health deterioration (weak health status)
Pyrexia (fever)
Scab (a hard coating on the skin formed during the wound healing)

10-19:

n/a

20-29:

Meningitis listeria (a bacterial infection of the membranes covering the brain and spinal cord (meninges))
Urticaria (rash of round, red welts on the skin that itch intensely)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Back pain
Cystitis (inflammation of the wall of the bladder)
Leukopenia (less number of white blood cells in blood)
Mastoiditis (infection of mastoid bone)
Neutropenia (an abnormally low number of neutrophils)
Rash
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)

30-39:

Feeling of despair
Suicidal ideation
Suicide attempt
Dizziness
Lacrimation increased
Nausea (feeling of having an urge to vomit)
Visual acuity reduced (reduced clearness of vision)

40-49:

Rash
Vasculitis (inflammation of a blood vessel or blood vessels)
Brain death
Circulatory collapse
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Palpitations (feelings or sensations that your heart is pounding or racing)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Infection
Petechiae (a small red or purple spot caused by bleeding into the skin)

50-59:

n/a

60+:

Asthenia (weakness)
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Febrile neutropenia (fever with reduced white blood cells)
Pneumonia
Ascites (accumulation of fluid in the abdominal cavity)
Delirium (wild excitement)
Subileus

What are the existing conditions these people have? *

Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 15.00%
Nausea (feeling of having an urge to vomit): 3 people, 15.00%
Hypokalemia (low potassium): 3 people, 15.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 15.00%
High Blood Pressure: 3 people, 15.00%
Lymphoma (cancer that begins in immune system cells): 2 people, 10.00%
Constipation: 2 people, 10.00%
Multiple Myeloma (cancer of the plasma cells): 2 people, 10.00%
Weight Decreased: 2 people, 10.00%
Neoplasm Malignant (cancer tumour): 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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