Zoloft and Zelboraf drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zoloft (sertraline hydrochloride) and Zelboraf (vemurafenib). Common drug interactions include death among females and rash among males.

The phase IV clinical study analyzes what interactions people have when they take Zoloft and Zelboraf. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,798 Zoloft users. Check the latest studies of Zoloft.

What is Zelboraf?

Zelboraf has active ingredients of vemurafenib. eHealthMe is studying from 8,392 Zelboraf users. Check the latest studies of Zelboraf.

On Jul, 19, 2026

18 people who take Zoloft and Zelboraf together, and have interactions are studied.

What are the common drug interactions of Zoloft and Zelboraf, by gender? *:

female:

Death
Angina pectoris (chest pain due to ischemia of the heart muscle)
Cardiac failure congestive
Electrocardiogram qt prolonged
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pneumonia
Acne (skin problems that cause pimples)
Alopecia (absence of hair from areas of the body)
Joint swelling
Peripheral swelling

male:

Rash
Back pain
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)
Asthma
Bipolar disorder (mood disorder)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Brain neoplasm (tumour of brain)
Burning sensation
Contusion (a type of hematoma of tissue in which capillaries)

What are the common drug interactions of Zoloft and Zelboraf, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Alopecia (absence of hair from areas of the body)
Photosensitivity reaction
Rash

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Cardiac failure congestive
Alopecia (absence of hair from areas of the body)
Fatigue (feeling of tiredness)
Joint swelling
Peripheral swelling
Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin)
Swelling face
Electrocardiogram qt prolonged
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

What are the existing conditions these people have? *

Malignant Melanoma (skin cancer rises from melancytes): 7 people, 38.89%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 4 people, 22.22%
High Blood Cholesterol: 2 people, 11.11%
Pain: 2 people, 11.11%
Hypersensitivity: 2 people, 11.11%
Stress And Anxiety: 1 person, 5.56%
Bipolar Disorder (mood disorder): 1 person, 5.56%
Bladder Disorder: 1 person, 5.56%
Brain Neoplasm Malignant (brain cancer tumour): 1 person, 5.56%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Zoloft and Zelboraf?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously