Zolpidem and Catapres drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zolpidem (zolpidem tartrate) and Catapres (clonidine hydrochloride). Common drug interactions include mitral valve prolapse among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Zolpidem and Catapres. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Zolpidem?

Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,696 Zolpidem users. Check the latest studies of Zolpidem.

What is Catapres?

Catapres has active ingredients of clonidine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 6,680 Catapres users. Check the latest studies of Catapres.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

52 people who take Zolpidem and Catapres together, and have interactions are studied.

Zolpidem and Catapres drug interactions.

What are the common drug interactions of Zolpidem and Catapres, by gender? *:

female:

Mitral valve prolapse (heart's mitral valve doesn't work well)
Nausea (feeling of having an urge to vomit)
Nerve injury
Oedema peripheral (superficial swelling)
Optic atrophy (the loss of a proportion of optic disc nerve fibres)
Osteoporosis (bones weak and more likely to break)
Pemphigoid (tense blisters on the skin)
Pericardial effusion (fluid around the heart)
Pericarditis (inflammation of the pericardium)
Peripheral ischaemia (impaired circulation to an extremity)

male:

Chronic kidney disease
Osteonecrosis (death of bone)
Pain
Renal impairment (severely reduced kidney function)
Renal injury (kidney injury)
Tooth loss
Acute respiratory failure
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Blood pressure fluctuation
Cardiac arrest

What are the common drug interactions of Zolpidem and Catapres, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)

30-39:

Anxiety
Chronic kidney disease
Emotional distress
Nephrogenic anaemia (anaemia due to kidney disease)
Pain
Pericardial effusion (fluid around the heart)
Pericarditis (inflammation of the pericardium)
Peroneal nerve palsy
Pleuritic pain
Pulmonary embolism (blockage of the main artery of the lung)

40-49:

Chronic kidney disease
Osteonecrosis (death of bone)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Blood creatinine increased
Bone density decreased
Emotional distress
Hip arthroplasty
Pain
Renal impairment (severely reduced kidney function)

50-59:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Wound
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Acute respiratory failure
Cardiac arrest
Cardiomyopathy (weakening of the heart muscle)
Device related infection
Disbacteriosis (a condition with microbial imbalances on or inside the body)

60+:

Renal failure (kidney dysfunction)
Asthenia (weakness)
Renal injury (kidney injury)
Abdominal tenderness
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthralgia (joint pain)
Ascites (accumulation of fluid in the abdominal cavity)
Back pain
Cataract (clouding of the lens inside the eye)
Cellulitis (infection under the skin)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 26.92%
Pain: 12 people, 23.08%
Multiple Myeloma (cancer of the plasma cells): 9 people, 17.31%
Sleep Disorder: 6 people, 11.54%
Infection: 5 people, 9.62%
High Blood Cholesterol: 5 people, 9.62%
Gout (uric acid crystals building up in the body): 4 people, 7.69%
Dizziness: 4 people, 7.69%
Diabetes: 4 people, 7.69%
Constipation: 4 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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