Dexedrine and Nicotrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dexedrine (dextroamphetamine sulfate) and Nicotrol (nicotine). Common drug interactions include abdominal discomfort among females and craniocerebral injury among males.

The phase IV clinical study analyzes what interactions people have when they take Dexedrine and Nicotrol. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Dexedrine?

Dexedrine has active ingredients of dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 4,735 Dexedrine users. Check the latest studies of Dexedrine.

What is Nicotrol?

Nicotrol has active ingredients of nicotine. eHealthMe is studying from 4,104 Nicotrol users. Check the latest studies of Nicotrol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

16 people who take Dexedrine and Nicotrol together, and have interactions are studied.

Dexedrine and Nicotrol drug interactions.

What are the common drug interactions of Dexedrine and Nicotrol, by gender? *:

female:

Abdominal discomfort
Anxiety
Coeliac disease (simple food intolerance)
Hemiplegic migraine (migraine attacks occurring in two or more people in the same family who experience weakness on one side of body)
Malaise (a feeling of general discomfort or uneasiness)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Sinusitis (inflammation of sinus)
Cataplexy (loss of muscle tone accompanied by full conscious awareness)
Migraine (headache)
Migraine with aura (headache with vision weakness)

male:

Craniocerebral injury (injury to cranium and brain)
Hypersomnia (excessive daytime sleepiness (eds))
Memory impairment
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Self-injurious ideation
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood testosterone decreased
Fall
Haemorrhage (bleeding)
Muscular weakness (muscle weakness)

What are the common drug interactions of Dexedrine and Nicotrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal discomfort
Anxiety
Migraine with aura (headache with vision weakness)
Self-injurious ideation
Coeliac disease (simple food intolerance)
Hemiplegic migraine (migraine attacks occurring in two or more people in the same family who experience weakness on one side of body)
Malaise (a feeling of general discomfort or uneasiness)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Sinusitis (inflammation of sinus)
Cataplexy (loss of muscle tone accompanied by full conscious awareness)

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 15 people, 93.75%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 14 people, 87.50%
Drowsiness: 2 people, 12.50%
Stress Symptoms: 1 person, 6.25%
Headache (pain in head): 1 person, 6.25%
Disturbance In Attention: 1 person, 6.25%
Depression: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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