Zometa and Piperacillin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Zometa (zoledronic acid) and Piperacillin (piperacillin sodium). Common drug interactions include thrombocytopenia among females and anxiety among males.
The phase IV clinical study analyzes what interactions people have when they take Zometa and Piperacillin. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.
What is Zometa?
Zometa has active ingredients of zoledronic acid. It is often used in multiple myeloma. eHealthMe is studying from 71,434 Zometa users. Check the latest studies of Zometa.
What is Piperacillin?
Piperacillin has active ingredients of piperacillin sodium. eHealthMe is studying from 5,597 Piperacillin users. Check the latest studies of Piperacillin.
33 people who take Zometa and Piperacillin together, and have interactions are studied.

What are the common drug interactions of Zometa and Piperacillin, by gender? *:
female:
- Thrombocytopenia (decrease of platelets in blood)
- Drug intolerance (drug sensitivity)
- Neutropenia (an abnormally low number of neutrophils)
- Pyrexia (fever)
- Cellulitis (infection under the skin)
- Constipation
- Diarrhoea
- Escherichia infection (bacterial infection by escherichia coli)
- Faecal incontinence (a lack of control over passing stool)
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
male:
- Anxiety
- Arthralgia (joint pain)
- Decreased interest
- Dehydration (dryness resulting from the removal of water)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diarrhoea
- Ejection fraction (the percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat)
- Extrasystoles
- Fatigue (feeling of tiredness)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
What are the common drug interactions of Zometa and Piperacillin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Myositis (inflammation of the muscles)
- Phlebitis (inflammation of the walls of a vein)
- Sepsis (a severe blood infection that can lead to organ failure and death)
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Cellulitis (infection under the skin)
- Constipation
- Diarrhoea
- Escherichia infection (bacterial infection by escherichia coli)
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Infection
- Klebsiella infection
- Lower respiratory tract infection
- Pneumonia
- Pyrexia (fever)
60+:
- Thrombocytopenia (decrease of platelets in blood)
- Drug intolerance (drug sensitivity)
- Anaemia (lack of blood)
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Aspartate aminotransferase increased
- Bone pain
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Interstitial lung disease
- Leukopenia (less number of white blood cells in blood)
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
What are the existing conditions these people have? *
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 11 people, 33.33%
- Anaemia (lack of blood): 9 people, 27.27%
- Infection: 8 people, 24.24%
- Itching: 8 people, 24.24%
- Rashes (redness): 8 people, 24.24%
- Haemorrhage (bleeding): 8 people, 24.24%
- Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 6 people, 18.18%
- Urinary Tract Infection: 6 people, 18.18%
- Pneumonia: 5 people, 15.15%
- Pain: 4 people, 12.12%
* Approximation only. Some reports may have incomplete information.
Do you take Zometa and Piperacillin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Zometa (71,434 reports)
- Piperacillin (5,597 reports)
Browse all drug interactions of Zometa and Piperacillin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Zometa:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Piperacillin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zometa and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Piperacillin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on zoledronic acid and piperacillin sodium (the active ingredients of Zometa and Piperacillin, respectively), and Zometa and Piperacillin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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