Zomig and Mirapex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zomig (zolmitriptan) and Mirapex (pramipexole dihydrochloride). Common drug interactions include ear pain among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Zomig and Mirapex. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Zomig?

Zomig has active ingredients of zolmitriptan. It is often used in migraine. eHealthMe is studying from 7,356 Zomig users. Check the latest studies of Zomig.

What is Mirapex?

Mirapex has active ingredients of pramipexole dihydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 20,622 Mirapex users. Check the latest studies of Mirapex.

On Jul, 09, 2026

30 people who take Zomig and Mirapex together, and have interactions are studied.

What are the common drug interactions of Zomig and Mirapex, by gender? *:

female:

Ear pain
Eustachian tube dysfunction (eustachian tube problems like clearing the ears when flying, suffering infection, and recurring ear infection)
Fall
Fibromyalgia (a long-term condition which causes pain all over the body)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
General physical health deterioration (weak health status)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Intervertebral disc degeneration (spinal disc degeneration)
Myalgia (muscle pain)
Myositis (inflammation of the muscles)

male:

Anxiety
Pain
Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
Back pain
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Bone disorder
Brain neoplasm (tumour of brain)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chest pain
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)

What are the common drug interactions of Zomig and Mirapex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
Pruritus (severe itching of the skin)

20-29:

n/a

30-39:

n/a

40-49:

Arthralgia (joint pain)
Back pain
Bone disorder
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Decreased interest
Disability
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Dry eye (lack of adequate tears)
Dry mouth
Dyslipidaemia (abnormal amount of lipids)

50-59:

Hypoaesthesia (reduced sense of touch or sensation)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

60+:

Anxiety
Pain
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
Back pain
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Bone disorder

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 13.33%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 13.33%
Depression: 4 people, 13.33%
Osteoporosis (bones weak and more likely to break): 3 people, 10.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 10.00%
Stress And Anxiety: 2 people, 6.67%
Pain: 2 people, 6.67%
Muscle Spasms (muscle contraction): 2 people, 6.67%
Hypersensitivity: 2 people, 6.67%
Asthma: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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