Zonegran and Ergocalciferol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Zonegran (zonisamide) and Ergocalciferol (ergocalciferol). Common drug interactions include bipolar disorder among females and headache among males.
The phase IV clinical study analyzes what interactions people have when they take Zonegran and Ergocalciferol. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.
What is Zonegran?
Zonegran has active ingredients of zonisamide. It is often used in epilepsy. eHealthMe is studying from 6,211 Zonegran users. Check the latest studies of Zonegran.
What is Ergocalciferol?
Ergocalciferol has active ingredients of ergocalciferol. It is often used in rickets. eHealthMe is studying from 32,652 Ergocalciferol users. Check the latest studies of Ergocalciferol.
32 people who take Zonegran and Ergocalciferol together, and have interactions are studied.

What are the common drug interactions of Zonegran and Ergocalciferol, by gender? *:
female:
- Bipolar disorder (mood disorder)
- Endometrial cancer
- Restless legs syndrome (a powerful urge to move your legs)
- Weight increased
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Urinary tract infection
- Drug effect decreased
- Hospitalisation
- Hypokalaemia (low potassium)
- Impaired work ability
male:
- Headache (pain in head)
- Back injury
- Intervertebral disc protrusion (spinal disc protrusion)
- Malaise (a feeling of general discomfort or uneasiness)
- Nausea (feeling of having an urge to vomit)
- Insomnia (sleeplessness)
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Decreased appetite
- Fall
What are the common drug interactions of Zonegran and Ergocalciferol, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Hypotonia (low muscle tone)
20-29:
- Back injury
- Headache (pain in head)
- Insomnia (sleeplessness)
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
30-39:
- Bipolar disorder (mood disorder)
- Endometrial cancer
- Restless legs syndrome (a powerful urge to move your legs)
- Weight increased
- Drug effect decreased
- Alopecia (absence of hair from areas of the body)
- Headache (pain in head)
- Insomnia (sleeplessness)
- Lethargy (tiredness)
- Nausea (feeling of having an urge to vomit)
40-49:
- Hypokalaemia (low potassium)
50-59:
- Impaired work ability
- Restless legs syndrome (a powerful urge to move your legs)
- Weight increased
- Decreased appetite
- Nausea (feeling of having an urge to vomit)
- Hospitalisation
- Hypokalaemia (low potassium)
- Bipolar disorder (mood disorder)
- Drug effect decreased
- Endometrial cancer
60+:
- Decreased interest
- Depressed mood
- Fall
- Head injury
- Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 16 people, 50.00%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 31.25%
- Migraine (headache): 3 people, 9.38%
- Headache (pain in head): 3 people, 9.38%
- Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 6.25%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 6.25%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 6.25%
- Drowsiness: 2 people, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Zonegran and Ergocalciferol?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Zonegran (6,211 reports)
- Ergocalciferol (32,652 reports)
Browse all drug interactions of Zonegran and Ergocalciferol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Zonegran:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ergocalciferol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zonegran and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ergocalciferol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Kapoor S, "Influence of Vitamin D Consumption and Levels on the Development of Psychiatric Disorders", Lee, Y. J., & Park, K. (2018). Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension.?Drug safety-case reports,?5(1), 7., 2014 Aug .
- Kapoor S, "Influence of Vitamin D Consumption and Levels on the Development of Psychiatric Disorders", Lee, Y. J., & Park, K. (2018). Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension.?Drug safety-case reports,?5(1), 7., 2014 Aug .
How the study uses the data?
The study uses data from the FDA. It is based on zonisamide and ergocalciferol (the active ingredients of Zonegran and Ergocalciferol, respectively), and Zonegran and Ergocalciferol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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