Zopiclone and Sectral drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zopiclone (eszopiclone) and Sectral (acebutolol hydrochloride). Common drug interactions include cholestasis among females and interstitial lung disease among males.

The phase IV clinical study analyzes what interactions people have when they take Zopiclone and Sectral. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Zopiclone?

Zopiclone has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 54,330 Zopiclone users. Check the latest studies of Zopiclone.

What is Sectral?

Sectral has active ingredients of acebutolol hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 3,548 Sectral users. Check the latest studies of Sectral.



On Jul, 11, 2026

27 people who take Zopiclone and Sectral together, and have interactions are studied.

Zopiclone and Sectral drug interactions.

What are the common drug interactions of Zopiclone and Sectral, by gender? *:

female:

  1. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  2. Bradypnoea (an abnormally slow respiratory rate)
  3. Coma (state of unconsciousness lasting more than six hours)
  4. Electrocardiogram qt prolonged
  5. Hepatitis (inflammation of the liver)
  6. Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
  7. Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)
  8. Suicide attempt
  9. Burning sensation
  10. Cytolytic hepatitis (dissolution or destruction of a liver cell)

male:

  1. Interstitial lung disease
  2. Drug level increased
  3. Erysipelas (bacterial skin infection)
  4. Fall
  5. Gastric ulcer (stomach ulcer)
  6. Haemoglobin decreased
  7. Influenza
  8. International normalised ratio increased
  9. Logorrhoea (excessive, uncontrollable, or incoherent talkativeness)
  10. Loss of consciousness

What are the common drug interactions of Zopiclone and Sectral, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Bradypnoea (an abnormally slow respiratory rate)
  2. Coma (state of unconsciousness lasting more than six hours)
  3. Electrocardiogram qt prolonged
  4. Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
  5. Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)
  6. Suicide attempt

50-59:

  1. Interstitial lung disease
  2. Drug level increased
  3. Hypotension (abnormally low blood pressure)
  4. Psychomotor skills impaired
  5. Oedema peripheral (superficial swelling)
  6. Orthopnoea (shortness of breath (dyspnea) when lying down)
  7. Suicide attempt
  8. Gastric ulcer (stomach ulcer)

60+:

  1. Arthralgia (joint pain)
  2. Burning sensation
  3. Haemoglobin decreased
  4. Headache (pain in head)
  5. Hepatitis (inflammation of the liver)
  6. Hot flush (sudden feelings of heat)
  7. Influenza
  8. International normalised ratio increased
  9. Interstitial lung disease
  10. Logorrhoea (excessive, uncontrollable, or incoherent talkativeness)

What are the existing conditions these people have? *

  1. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 5 people, 18.52%
  2. Suicide Attempt: 3 people, 11.11%
  3. Breast Cancer Metastatic: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Zopiclone and Sectral?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zopiclone and Sectral:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zopiclone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sectral:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zopiclone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sectral and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on eszopiclone and acebutolol hydrochloride (the active ingredients of Zopiclone and Sectral, respectively), and Zopiclone and Sectral (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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