Bupropion hydrochloride and Psychomotor hyperactivity - a phase IV clinical study of FDA data

Summary:

Psychomotor hyperactivity is reported as a side effect among people who take Bupropion hydrochloride (bupropion hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Pantoprazole, and have Major depression.

The phase IV clinical study analyzes which people have Psychomotor hyperactivity when taking Bupropion hydrochloride. It is created by eHealthMe based on reports of 18,551 people who have side effects when taking Bupropion hydrochloride from the FDA, and is updated regularly.

What is Bupropion hydrochloride?

Bupropion hydrochloride has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 21,496 Bupropion hydrochloride users. Check the latest studies of Bupropion hydrochloride.

What is Psychomotor hyperactivity?

Psychomotor hyperactivity (feelings of extreme restlessness) is found to be associated with 889 drugs and 1,101 conditions by eHealthMe. Check the latest studies of Psychomotor hyperactivity.

On Jul, 11, 2026

18,551 people reported to have side effects when taking Bupropion hydrochloride.
Among them, 64 people (0.34%) have Psychomotor hyperactivity.

Could Bupropion hydrochloride cause Psychomotor hyperactivity?

Among these 64 people:

How long have people been on Bupropion hydrochloride when they have Psychomotor hyperactivity? *

What is the gender of people who have Psychomotor hyperactivity when taking Bupropion hydrochloride? *

female: 58.49 %
male: 41.51 %

What is the age of people who have Psychomotor hyperactivity when taking Bupropion hydrochloride? *

What are other drugs people take besides Bupropion hydrochloride? *

Pantoprazole: 8 people, 12.50%
Estrace: 5 people, 7.81%
Synthroid: 5 people, 7.81%
Prilosec: 5 people, 7.81%
Alprazolam: 5 people, 7.81%
Sertraline Hydrochloride: 5 people, 7.81%
Colace: 5 people, 7.81%
Fosamax: 5 people, 7.81%
Enoxaparin Sodium: 5 people, 7.81%
Zolpidem Tartrate: 4 people, 6.25%

What are other side effects people have besides Psychomotor hyperactivity? *

Insomnia (sleeplessness): 21 people, 32.81%
Agitation (state of anxiety or nervous excitement): 17 people, 26.56%
Irritability: 12 people, 18.75%
Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 11 people, 17.19%
Overdose: 10 people, 15.62%
Dyspnea (difficult or laboured breathing): 10 people, 15.62%
Suicidal Ideation: 10 people, 15.62%
Fatigue (feeling of tiredness): 9 people, 14.06%
Acute Myocardial Infarction (acute heart attack): 9 people, 14.06%
Drug Ineffective: 9 people, 14.06%

What are the existing conditions these people have? *

Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 9 people, 14.06%
Quit Smoking: 6 people, 9.38%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 5 people, 7.81%
Insomnia (sleeplessness): 5 people, 7.81%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 5 people, 7.81%
Osteopenia (a condition where bone mineral density is lower than normal): 5 people, 7.81%
Fatigue (feeling of tiredness): 3 people, 4.69%
Ill-Defined Disorder: 2 people, 3.12%
Bipolar Disorder (mood disorder): 2 people, 3.12%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Bupropion hydrochloride and have Psychomotor hyperactivity?

- Check whether Psychomotor hyperactivity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bupropion hydrochloride:

Bupropion hydrochloride (21,496 reports)

Browse all side effects of Bupropion hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Psychomotor hyperactivity:

Psychomotor hyperactivity (889 drugs)

Browse all the conditions that are associated with Psychomotor hyperactivity:

Psychomotor hyperactivity (1,101 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on bupropion hydrochloride (the active ingredients of Bupropion hydrochloride) and Bupropion hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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