Zosyn and Abacavir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zosyn (piperacillin sodium; tazobactam sodium) and Abacavir (abacavir sulfate). Common drug interactions include aids dementia complex among females and adrenal insufficiency among males.

The phase IV clinical study analyzes what interactions people have when they take Zosyn and Abacavir. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Zosyn?

Zosyn has active ingredients of piperacillin sodium; tazobactam sodium. It is often used in pneumonia. eHealthMe is studying from 10,236 Zosyn users. Check the latest studies of Zosyn.

What is Abacavir?

Abacavir has active ingredients of abacavir sulfate. It is often used in hiv infection. eHealthMe is studying from 8,306 Abacavir users. Check the latest studies of Abacavir.

On Jul, 16, 2026

13 people who take Zosyn and Abacavir together, and have interactions are studied.

What are the common drug interactions of Zosyn and Abacavir, by gender? *:

female:

Aids dementia complex (most common and clinically important cns complications of late hiv-1 infection)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

male:

Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Hepatic enzyme increased
Pain
Renal tubular necrosis (death of kidney tubules)
Bone density decreased
Bradycardia (abnormally slow heart action)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Depression
Femur fracture
Hip fracture

What are the common drug interactions of Zosyn and Abacavir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Lymphadenopathy (disease or enlargement of lymph nodes)
T-cell lymphoma (a blood cell cancer)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress
Injury
Osteonecrosis (death of bone)
Pain
Renal tubular necrosis (death of kidney tubules)

50-59:

Type iv hypersensitivity reaction (delayed type hypersensitivity as the reaction takes two to three days to develop)

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Emotional distress
Femur fracture
Hip fracture
Osteoporosis (bones weak and more likely to break)

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 7.69%
Pulmonary Embolism (blockage of the main artery of the lung): 1 person, 7.69%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.69%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 1 person, 7.69%
Cd4 Lymphocytes Decreased: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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