Zyflo and Dexilant drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyflo (zileuton) and Dexilant (dexlansoprazole). Common drug interactions include asthma among females.

The phase IV clinical study analyzes what interactions people have when they take Zyflo and Dexilant. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Zyflo?

Zyflo has active ingredients of zileuton. eHealthMe is studying from 1,004 Zyflo users. Check the latest studies of Zyflo.

What is Dexilant?

Dexilant has active ingredients of dexlansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 57,103 Dexilant users. Check the latest studies of Dexilant.

On Jul, 12, 2026

40 people who take Zyflo and Dexilant together, and have interactions are studied.

What are the common drug interactions of Zyflo and Dexilant, by gender? *:

female:

Asthma
Pneumonia
Menopause (end of monthly cycles in women)
Rhinitis allergic (inflammation of the nasal airways due to allergy)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Inflammation
Oesophageal spasm (contraction of oesophagus)
Pharyngeal erythema (pharyngeal redness)
Pleurisy (inflammation of the pleurae, which causes pain when breathing)
Somnolence (a state of near-sleep, a strong desire for sleep)

male:

n/a

What are the common drug interactions of Zyflo and Dexilant, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Rhinitis allergic (inflammation of the nasal airways due to allergy)
Aspartate aminotransferase decreased
Asthma
Catheter site infection (infection at the site of insertion)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Dyspnoea (difficult or laboured respiration)
Eye pruritus (eye itching)
Increased viscosity of bronchial secretion
Lacrimation increased
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

40-49:

Asthma
Fatigue (feeling of tiredness)
Malaise (a feeling of general discomfort or uneasiness)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)

50-59:

Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Drug ineffective
Drug tolerance decreased
Oesophageal spasm (contraction of oesophagus)
Pleurisy (inflammation of the pleurae, which causes pain when breathing)
Restless legs syndrome (a powerful urge to move your legs)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Somnolence (a state of near-sleep, a strong desire for sleep)
Stress

60+:

Asthma
Pneumonia
Injection site bruising
Vasculitis (inflammation of a blood vessel or blood vessels)
Arthralgia (joint pain)
Cough
Dyspnoea (difficult or laboured respiration)
Immunodeficiency
Paranasal sinus discomfort
Sinusitis (inflammation of sinus)

What are the existing conditions these people have? *

Asthma: 23 people, 57.50%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 35.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 14 people, 35.00%
Stress And Anxiety: 2 people, 5.00%
Pseudomonas Bronchitis (bronchitis by bacterium (genus pseudomonas) of a genus that occurs in soil and detritus): 2 people, 5.00%
Hiv Infection: 2 people, 5.00%
Dyspnea (difficult or laboured breathing): 2 people, 5.00%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 5.00%
Allergic Rhinitis: 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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