Zykadia and Pemetrexed drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zykadia (ceritinib) and Pemetrexed (pemetrexed). Common drug interactions include malignant neoplasm progression among females and liver disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Zykadia and Pemetrexed. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Zykadia?

Zykadia has active ingredients of ceritinib. eHealthMe is studying from 2,091 Zykadia users. Check the latest studies of Zykadia.

What is Pemetrexed?

Pemetrexed has active ingredients of pemetrexed. eHealthMe is studying from 17,491 Pemetrexed users. Check the latest studies of Pemetrexed.

On Jul, 08, 2026

14 people who take Zykadia and Pemetrexed together, and have interactions are studied.

Zykadia and Pemetrexed drug interactions.

What are the common drug interactions of Zykadia and Pemetrexed, by gender? *:

female:

Malignant neoplasm progression (cancer tumour came back)
Nausea (feeling of having an urge to vomit)
Non-small cell lung cancer (type of epithelial lung cancer)
Weight decreased
Metastases to central nervous system (cancer spreads to central nervous system)
Death
Decreased appetite
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Gastrointestinal toxicity (damage to digestive tract by any substance)

male:

Liver disorder (liver diseases)
Lung disorder (lung disease)
Non-small cell lung cancer (type of epithelial lung cancer)
Non-small cell lung cancer metastatic (type of epithelial lung cancer spreads to other parts)
Peripheral sensory neuropathy (damage to one or more of your peripheral nerves)
Thrombocytopenia (decrease of platelets in blood)
Visual impairment
Anaemia (lack of blood)
Blindness unilateral
Death

What are the common drug interactions of Zykadia and Pemetrexed, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Lymphocyte count decreased
Malignant neoplasm progression (cancer tumour came back)
Metastases to central nervous system (cancer spreads to central nervous system)
Muscular weakness (muscle weakness)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Non-small cell lung cancer stage iv
Oedema (fluid collection in tissue)
Partial seizures (seizures which affect only a part of the brain at onset)
Platelet count decreased

40-49:

Liver disorder (liver diseases)
Lung disorder (lung disease)

50-59:

General physical health deterioration (weak health status)
Infection
Lung infiltration malignant (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung can cause cancer)
Malignant neoplasm progression (cancer tumour came back)
Nausea (feeling of having an urge to vomit)
Non-small cell lung cancer (type of epithelial lung cancer)
Weight decreased
Death
Decreased appetite
Dyspnoea (difficult or laboured respiration)

60+:

Anaemia (lack of blood)
Death
Metastases to adrenals (cancer spreads to adrenal gland of kidney)
Non-small cell lung cancer (type of epithelial lung cancer)
Thrombocytopenia (decrease of platelets in blood)

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 5 people, 35.71%
Non-Small Cell Lung Cancer Stage Iv: 3 people, 21.43%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 14.29%
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue): 2 people, 14.29%
Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 1 person, 7.14%
Nausea And Vomiting: 1 person, 7.14%
Nausea (feeling of having an urge to vomit): 1 person, 7.14%
Lung Carcinoma Cell Type Unspecified Stage Iv (the lung cancer has spread to other organs of the body, such as the other lung, brain, or liver): 1 person, 7.14%
Lung Adenocarcinoma Stage Iv (the cancer has spread to other organs of the body, such as the other lung, brain, or liver): 1 person, 7.14%
Lung Adenocarcinoma (a form of non-small cell lung cancer): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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