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Ritalin and Grand mal convulsion - a phase IV clinical study of FDA data

Summary:

Grand mal convulsion is reported as a side effect among people who take Ritalin (methylphenidate hydrochloride), especially for people who are male, 10-19 old, have been taking the drug for < 1 month also take Prozac, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Grand mal convulsion when taking Ritalin. It is created by eHealthMe based on reports of 26,179 people who have side effects when taking Ritalin from the FDA, and is updated regularly.

What is Ritalin?

Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 29,427 Ritalin users. Check the latest studies of Ritalin.

What is Grand mal convulsion?

Grand mal convulsion (a type of generalized seizure that affects the entire brain) is found to be associated with 923 drugs and 1,337 conditions by eHealthMe. Check the latest studies of Grand mal convulsion.

On Jul, 08, 2026

26,179 people reported to have side effects when taking Ritalin.
Among them, 51 people (0.19%) have Grand mal convulsion.

Could Ritalin cause Grand mal convulsion?

Among these 51 people:

How long have people been on Ritalin when they have Grand mal convulsion? *

  • < 1 month: 50 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 25 %
  • 1 - 2 years: 25 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Grand mal convulsion when taking Ritalin? *

  • female: 45.1 %
  • male: 54.9 %

What is the age of people who have Grand mal convulsion when taking Ritalin? *

  • 0-1: 0.0 %
  • 2-9: 12.2 %
  • 10-19: 26.83 %
  • 20-29: 12.2 %
  • 30-39: 9.76 %
  • 40-49: 14.63 %
  • 50-59: 12.2 %
  • 60+: 12.2 %

What are other drugs people take besides Ritalin? *

  1. Prozac: 11 people, 21.57%
  2. Seroquel: 7 people, 13.73%
  3. Ativan: 7 people, 13.73%
  4. Paxil: 6 people, 11.76%
  5. Neurontin: 6 people, 11.76%
  6. Remeron: 6 people, 11.76%
  7. Decadron: 5 people, 9.80%
  8. Wellbutrin Sr: 5 people, 9.80%
  9. Clonidine: 5 people, 9.80%
  10. Lasix: 5 people, 9.80%

What are other side effects people have besides Grand mal convulsion? *

  1. Fatigue (feeling of tiredness): 7 people, 13.73%
  2. Fever: 5 people, 9.80%
  3. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 5 people, 9.80%
  4. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 5 people, 9.80%
  5. Hypoaesthesia (reduced sense of touch or sensation): 4 people, 7.84%
  6. Cerebral Infarction (less blood supply to brain resulting tissue damage): 4 people, 7.84%
  7. Loss Of Consciousness: 4 people, 7.84%
  8. The Flu (the flu is caused by an influenza virus): 4 people, 7.84%
  9. Heart Attack: 4 people, 7.84%
  10. Fainting (loss of consciousness and postural tone): 3 people, 5.88%

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 13.73%
  2. Headache (pain in head): 2 people, 3.92%
  3. Pain: 2 people, 3.92%
  4. Migraine (headache): 2 people, 3.92%
  5. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 2 people, 3.92%
  6. Gastric Cancer (stomach cancer): 2 people, 3.92%
  7. Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 1 person, 1.96%
  8. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 1.96%
  9. Bipolar Disorder (mood disorder): 1 person, 1.96%
  10. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 1.96%

* Approximation only. Some reports may have incomplete information.

Do you take Ritalin and have Grand mal convulsion?

- Check whether Grand mal convulsion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ritalin:

Grand mal convulsion treatments and more:

How severe was Grand mal convulsion and when was it recovered:

Expand to all the drugs that have ingredients of methylphenidate hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ritalin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Grand mal convulsion:

Browse all the conditions that are associated with Grand mal convulsion:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate hydrochloride (the active ingredients of Ritalin) and Ritalin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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