Zyprexa and Emcyt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyprexa (olanzapine) and Emcyt (estramustine phosphate sodium). Common drug interactions include abdominal pain among females and somnolence among males.

The phase IV clinical study analyzes what interactions people have when they take Zyprexa and Emcyt. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Zyprexa?

Zyprexa has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 64,724 Zyprexa users. Check the latest studies of Zyprexa.

What is Emcyt?

Emcyt has active ingredients of estramustine phosphate sodium. eHealthMe is studying from 508 Emcyt users. Check the latest studies of Emcyt.



On Jul, 08, 2026

13 people who take Zyprexa and Emcyt together, and have interactions are studied.

Zyprexa and Emcyt drug interactions.

What are the common drug interactions of Zyprexa and Emcyt, by gender? *:

female:

  1. Abdominal pain
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Anaemia (lack of blood)
  4. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  5. Aortic arteriosclerosis (hardening of the aortic arteries)
  6. Aphasia (damage to the parts of the brain that control language)
  7. Back pain
  8. Benign prostatic hyperplasia (benign enlargement of the prostate)
  9. Bone disorder
  10. Bone loss

male:

  1. Somnolence (a state of near-sleep, a strong desire for sleep)
  2. Anaemia (lack of blood)
  3. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  4. Weight decreased
  5. Aphasia (damage to the parts of the brain that control language)
  6. Loss of consciousness
  7. Abdominal discomfort
  8. Abdominal pain
  9. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  10. Anhedonia (inability to experience pleasure from activities usually found enjoyable)

What are the common drug interactions of Zyprexa and Emcyt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Dysarthria (speech disorder)
  2. Hypertension (high blood pressure)
  3. Pain
  4. Abdominal discomfort
  5. Abdominal pain
  6. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  7. Anaemia (lack of blood)
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  9. Aortic arteriosclerosis (hardening of the aortic arteries)
  10. Aphasia (damage to the parts of the brain that control language)

50-59:

  1. Death
  2. Decreased interest
  3. Emotional distress
  4. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  5. General physical health deterioration (weak health status)
  6. Gingival disorder (gum disease)
  7. Hallucination, visual (seeing things that aren't there)
  8. Hypoaesthesia (reduced sense of touch or sensation)
  9. Impaired healing
  10. Jaw disorder (jaw disease)

60+:

  1. Aphasia (damage to the parts of the brain that control language)
  2. Loss of consciousness
  3. Bowel movement irregularity
  4. Cellulitis (infection under the skin)
  5. Cerebral atrophy (decrement in size of brain)
  6. Cerebral infarction (less blood supply to brain resulting tissue damage)
  7. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  8. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  9. Decreased appetite
  10. Dermal cyst

What are the existing conditions these people have? *

  1. Prostate Cancer: 4 people, 30.77%
  2. Nausea (feeling of having an urge to vomit): 4 people, 30.77%
  3. Metastases To Bone (cancer spreads to bone): 4 people, 30.77%
  4. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 7.69%
  5. Pain In Extremity: 1 person, 7.69%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%
  7. Depression: 1 person, 7.69%
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zyprexa and Emcyt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zyprexa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Emcyt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zyprexa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Emcyt and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on olanzapine and estramustine phosphate sodium (the active ingredients of Zyprexa and Emcyt, respectively), and Zyprexa and Emcyt (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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