Zyprexa and Erbitux drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Zyprexa (olanzapine) and Erbitux (cetuximab). Common drug interactions include endocarditis among females and asthenia among males.
The phase IV clinical study analyzes what interactions people have when they take Zyprexa and Erbitux. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Zyprexa?
Zyprexa has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 64,724 Zyprexa users. Check the latest studies of Zyprexa.
What is Erbitux?
Erbitux has active ingredients of cetuximab. It is often used in cancer. eHealthMe is studying from 19,276 Erbitux users. Check the latest studies of Erbitux.
13 people who take Zyprexa and Erbitux together, and have interactions are studied.

What are the common drug interactions of Zyprexa and Erbitux, by gender? *:
female:
- Endocarditis (inflammation in heart muscle)
- Platelet count decreased
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Pyrexia (fever)
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Nausea (feeling of having an urge to vomit)
- Anaemia (lack of blood)
- Asthenia (weakness)
- Confusional state
male:
- Asthenia (weakness)
- Confusional state
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Vomiting
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Fatigue (feeling of tiredness)
- Gastrointestinal necrosis (destruction of gastrointestinal organ)
- Hyperthermia (body temperature greatly above normal)
- Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
- Overdose
What are the common drug interactions of Zyprexa and Erbitux, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Dyspnoea (difficult or laboured respiration)
40-49:
- Asthenia (weakness)
- Confusional state
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Fatigue (feeling of tiredness)
- Hyperthermia (body temperature greatly above normal)
- Overdose
- Rash
- Renal failure (kidney dysfunction)
- Respiratory rate decreased (less breathing rate/min)
- Somnolence (a state of near-sleep, a strong desire for sleep)
50-59:
- Asthenia (weakness)
- Optic neuritis (optic nerve inflammation)
60+:
- Endocarditis (inflammation in heart muscle)
- Platelet count decreased
- Diarrhoea
- Disease progression
- Gastrointestinal necrosis (destruction of gastrointestinal organ)
- Haematuria (presence of blood in urine)
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
- Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
What are the existing conditions these people have? *
- Colon Cancer: 4 people, 30.77%
- Rectal Cancer (cancer of rectum): 3 people, 23.08%
- Cancer Pain: 3 people, 23.08%
- Hypopharyngeal Cancer: 2 people, 15.38%
- Tumor: 1 person, 7.69%
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 7.69%
- Nausea (feeling of having an urge to vomit): 1 person, 7.69%
- Insomnia (sleeplessness): 1 person, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Zyprexa and Erbitux?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Zyprexa and Erbitux:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Zyprexa:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Erbitux:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zyprexa and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Erbitux and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Gupta SK, Shwetank B, "Reversible bilateral sensori-neural hearing loss due to olanzapine in a male suffering from bipolar affective disorder", Indian journal of pharmacology, 2014 Jan .
- Og?odek E, Szota A, Araszkiewicz A, "Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment", Aust NZJ Psychiatry, 2013 Oct .
- Gupta D, Shukla P, Bisht SS, Bhatt ML, Pant MC, Srivastava K, "Deep vein and artery thrombosis associated with cetuximab-based chemoradiotherapy", Indian journal of pharmacology, 2011 Jan .
- Gupta SK, Shwetank B, "Reversible bilateral sensori-neural hearing loss due to olanzapine in a male suffering from bipolar affective disorder", Indian journal of pharmacology, 2014 Jan .
- Og?odek E, Szota A, Araszkiewicz A, "Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment", Aust NZJ Psychiatry, 2013 Oct .
- Gupta D, Shukla P, Bisht SS, Bhatt ML, Pant MC, Srivastava K, "Deep vein and artery thrombosis associated with cetuximab-based chemoradiotherapy", Indian journal of pharmacology, 2011 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on olanzapine and cetuximab (the active ingredients of Zyprexa and Erbitux, respectively), and Zyprexa and Erbitux (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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