Zyprexa and Sensipar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyprexa (olanzapine) and Sensipar (cinacalcet hydrochloride). Common drug interactions include death among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Zyprexa and Sensipar. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Zyprexa?

Zyprexa has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 64,724 Zyprexa users. Check the latest studies of Zyprexa.

What is Sensipar?

Sensipar has active ingredients of cinacalcet hydrochloride. It is often used in hyperparathyroidism secondary. eHealthMe is studying from 46,034 Sensipar users. Check the latest studies of Sensipar.

On Jul, 25, 2026

13 people who take Zyprexa and Sensipar together, and have interactions are studied.

What are the common drug interactions of Zyprexa and Sensipar, by gender? *:

female:

Death
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Dehydration (dryness resulting from the removal of water)
Delirium (wild excitement)
Diabetes mellitus inadequate control
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Disease progression
Disturbance in attention
Dry gangrene (diminished blood supply due to vascular problems)

male:

Abdominal distension
Ascites (accumulation of fluid in the abdominal cavity)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Pain in extremity
Pancreatitis (inflammation of pancreas)
Pancreatitis chronic (chronic inflammation of pancreas)
Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)
Renal failure (kidney dysfunction)
Renal failure chronic (long lasting kidney dysfunction)
Suicidal ideation

What are the common drug interactions of Zyprexa and Sensipar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Asthenia (weakness)
Cardiac failure congestive
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Chest pain
Decreased appetite
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Flushing (the warm, red condition of human skin)
Hyperhidrosis (abnormally increased sweating)
Hypotension (abnormally low blood pressure)

50-59:

Abdominal distension
Ascites (accumulation of fluid in the abdominal cavity)
Asterixis (flapping tremor, or liver flap)
Atrioventricular block first degree (heart block first degree)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Catheter sepsis (bacterial infection in blood due to catheter)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dysarthria (speech disorder)

60+:

Acute respiratory failure
Anaphylactic reaction (serious allergic reaction)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Swelling face
Unresponsive to stimuli
Angioedema (rapid swelling of the dermis)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspnoea (difficult or laboured respiration)
Hypotension (abnormally low blood pressure)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)

What are the existing conditions these people have? *

Nephrogenic Anaemia (anaemia due to kidney disease): 1 person, 7.69%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 1 person, 7.69%
High Blood Pressure: 1 person, 7.69%
Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 1 person, 7.69%
Depression: 1 person, 7.69%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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