Zyrtec and Corgard drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyrtec (cetirizine hydrochloride) and Corgard (nadolol). Common drug interactions include cardiac failure congestive among females and cholelithiasis among males.

The phase IV clinical study analyzes what interactions people have when they take Zyrtec and Corgard. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Zyrtec?

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,620 Zyrtec users. Check the latest studies of Zyrtec.

What is Corgard?

Corgard has active ingredients of nadolol. It is often used in high blood pressure. eHealthMe is studying from 3,342 Corgard users. Check the latest studies of Corgard.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

58 people who take Zyrtec and Corgard together, and have interactions are studied.

What are the common drug interactions of Zyrtec and Corgard, by gender? *:

female:

Cardiac failure congestive
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Cerebral atrophy (decrement in size of brain)
Chest discomfort
Chronic kidney disease
Clostridium difficile sepsis (infection(pus formation) of colon by clostridium difficile bacteria)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Depression
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Diarrhoea

male:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Coma (state of unconsciousness lasting more than six hours)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Conjunctivitis (pink eye)
Dizziness
Dyspepsia (indigestion)
Eye infection bacterial
Liver transplant
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Pharyngolaryngeal pain

What are the common drug interactions of Zyrtec and Corgard, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Hepatic necrosis (large portions of liver die off due to severe liver disease)
Hepatitis (inflammation of the liver)
Pleural effusion (water on the lungs)
Ascites (accumulation of fluid in the abdominal cavity)
Headache (pain in head)
Myalgia (muscle pain)
Pain
Breath sounds decreased
Crepitations (noises are produced by the rubbing of parts one against the other)
Hepatomegaly (abnormal enlargement of the liver)

30-39:

n/a

40-49:

Headache (pain in head)
Urticaria (rash of round, red welts on the skin that itch intensely)
Hepatitis (inflammation of the liver)
Drug ineffective

50-59:

Osteopenia (a condition where bone mineral density is lower than normal)
Foot fracture
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Osteoporosis (bones weak and more likely to break)
Pain
Pain in extremity
Accident
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
Impaired healing
Skin ulcer

60+:

Dizziness
Encephalopathy (functioning of the brain is affected by some agent or condition)
Sedation
Shoulder operation
Upper limb fracture
Fatigue (feeling of tiredness)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Back pain
Conjunctivitis (pink eye)
Contusion (a type of hematoma of tissue in which capillaries)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 15.52%
Headache (pain in head): 7 people, 12.07%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 6.90%
Pain: 4 people, 6.90%
Cardiac Disorder: 4 people, 6.90%
Tension Headache: 3 people, 5.17%
Multiple Allergies (allergy to multiple agents): 3 people, 5.17%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 5.17%

* Approximation only. Some reports may have incomplete information.

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