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Zyrtec and Estrone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyrtec (cetirizine hydrochloride) and Estrone (estrone). Common drug interactions include gastrooesophageal reflux disease among females.

The phase IV clinical study analyzes what interactions people have when they take Zyrtec and Estrone. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Zyrtec?

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,619 Zyrtec users. Check the latest studies of Zyrtec.

What is Estrone?

Estrone has active ingredients of estrone. eHealthMe is studying from 225 Estrone users. Check the latest studies of Estrone.

On Jul, 17, 2026

12 people who take Zyrtec and Estrone together, and have interactions are studied.

Zyrtec and Estrone drug interactions.

What are the common drug interactions of Zyrtec and Estrone, by gender? *:

female:

  1. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  2. Weight increased
  3. Hyperthyroidism (over activity of the thyroid gland)
  4. Insomnia (sleeplessness)
  5. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  6. Neuropathy peripheral (surface nerve damage)
  7. Peripheral swelling
  8. Spinal column stenosis (narrowing of spinal column)
  9. Suicidal ideation
  10. Thymoma (a tumour originating from the epithelial cells of the thymus)

male:

n/a

What are the common drug interactions of Zyrtec and Estrone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Breast cancer
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Glaucoma (increased fluid pressure in the eye with vision loss)
  4. Hypertension (high blood pressure)
  5. Hyperthyroidism (over activity of the thyroid gland)
  6. Neuropathy peripheral (surface nerve damage)
  7. Palpitations (feelings or sensations that your heart is pounding or racing)
  8. Thymoma (a tumour originating from the epithelial cells of the thymus)
  9. Weight increased

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 100.00%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 12 people, 100.00%
  3. Stress And Anxiety: 1 person, 8.33%
  4. Insomnia (sleeplessness): 1 person, 8.33%
  5. Drowsiness: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Zyrtec and Estrone?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zyrtec and Estrone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zyrtec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Estrone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zyrtec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Estrone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cetirizine hydrochloride and estrone (the active ingredients of Zyrtec and Estrone, respectively), and Zyrtec and Estrone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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