Zyrtec and Multihance drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyrtec (cetirizine hydrochloride) and Multihance (gadobenate dimeglumine). Common drug interactions include oedema among females and nephrogenic systemic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Zyrtec and Multihance. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Zyrtec?

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,619 Zyrtec users. Check the latest studies of Zyrtec.

What is Multihance?

Multihance has active ingredients of gadobenate dimeglumine. eHealthMe is studying from 5,786 Multihance users. Check the latest studies of Multihance.

On Jul, 12, 2026

19 people who take Zyrtec and Multihance together, and have interactions are studied.

Zyrtec and Multihance drug interactions.

What are the common drug interactions of Zyrtec and Multihance, by gender? *:

female:

Oedema (fluid collection in tissue)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Rash macular (small, flat red spots)
Skin atrophy (wasting of skin)
Skin exfoliation (removal of the oldest dead skin cells)
Skin haemorrhage (bleeding into skin)
Skin tightness
Systemic sclerosis (an autoimmune or connective tissue disease. it is characterized by thickening of the skin)
Emotional distress
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

male:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Arthralgia (joint pain)
Hypoaesthesia (reduced sense of touch or sensation)
Joint contracture (a permanent shortening of a muscle or joint)
Joint range of motion decreased (disease of joint movement)
Muscular weakness (muscle weakness)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Oedema peripheral (superficial swelling)
Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

What are the common drug interactions of Zyrtec and Multihance, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Blood triglycerides increased

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain upper
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthralgia (joint pain)
Burning sensation
Contusion (a type of hematoma of tissue in which capillaries)
Dry skin
Dysstasia (difficulty in standing)
Emotional distress
Fatigue (feeling of tiredness)

50-59:

Anxiety
Emotional distress
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Gait disturbance
General physical health deterioration (weak health status)
Hyperaesthesia
Joint range of motion decreased (disease of joint movement)
Mobility decreased (ability to move is reduced)
Muscle tightness
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

60+:

Hypersensitivity
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
General physical health deterioration (weak health status)
Injury
Mobility decreased (ability to move is reduced)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Oedema peripheral (superficial swelling)
Pain
Pain in extremity
Pulmonary hypertension (increase in blood pressure in the lung artery)

What are the existing conditions these people have? *

Anaemia (lack of blood): 8 people, 42.11%
Asthma: 7 people, 36.84%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 36.84%
Multiple Allergies (allergy to multiple agents): 7 people, 36.84%
Osteomyelitis (infection of bone): 3 people, 15.79%
Nuclear Magnetic Resonance Imaging Brain: 2 people, 10.53%
Hyperpituitarism (excessive activity of the pituitary gland): 1 person, 5.26%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 5.26%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 5.26%
High Blood Cholesterol: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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