Zyrtec and Perphenazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyrtec (cetirizine hydrochloride) and Perphenazine (perphenazine). Common drug interactions include chronic kidney disease among females and abdominal pain upper among males.

The phase IV clinical study analyzes what interactions people have when they take Zyrtec and Perphenazine. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Zyrtec?

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,619 Zyrtec users. Check the latest studies of Zyrtec.

What is Perphenazine?

Perphenazine has active ingredients of perphenazine. It is often used in bipolar i disorder. eHealthMe is studying from 2,712 Perphenazine users. Check the latest studies of Perphenazine.

On Jul, 13, 2026

21 people who take Zyrtec and Perphenazine together, and have interactions are studied.

Zyrtec and Perphenazine drug interactions.

What are the common drug interactions of Zyrtec and Perphenazine, by gender? *:

female:

Chronic kidney disease
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Renal failure (kidney dysfunction)
Dysphagia (a condition in which swallowing is difficult or painful)
Allergy to animal
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)
Asthma
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

male:

Abdominal pain upper
Abnormal behaviour
Pruritus (severe itching of the skin)
Tremor (trembling or shaking movements in one or more parts of your body)
Type 2 diabetes mellitus
Aggression
Chest pain
Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetes with hyperosmolarity (diabetes with increasing blood glucose levels and dehydration)

What are the common drug interactions of Zyrtec and Perphenazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abnormal behaviour
Aggression
Pruritus (severe itching of the skin)

20-29:

n/a

30-39:

n/a

40-49:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetes with hyperosmolarity (diabetes with increasing blood glucose levels and dehydration)
Type 2 diabetes mellitus

50-59:

Chronic kidney disease
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetes mellitus inadequate control
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Renal failure (kidney dysfunction)
Type 1 diabetes mellitus
Type 2 diabetes mellitus

60+:

Chronic kidney disease
Abdominal pain upper
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Renal failure (kidney dysfunction)
Tremor (trembling or shaking movements in one or more parts of your body)
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anxiety
Aortic valve incompetence
Cardiac arrest

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 28.57%
Pain: 4 people, 19.05%
High Blood Pressure: 4 people, 19.05%
Stress And Anxiety: 2 people, 9.52%
Psychotic Disorder: 2 people, 9.52%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 9.52%
Infection: 2 people, 9.52%
Hypersensitivity: 2 people, 9.52%
High Blood Cholesterol: 2 people, 9.52%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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