Zyvox and Clonidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyvox (linezolid) and Clonidine (clonidine). Common drug interactions include diarrhoea haemorrhagic among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Zyvox and Clonidine. It is created by eHealthMe based on reports of 81 people who take the same drugs from the FDA, and is updated regularly.

What is Zyvox?

Zyvox has active ingredients of linezolid. It is often used in mrsa infection. eHealthMe is studying from 9,399 Zyvox users. Check the latest studies of Zyvox.

What is Clonidine?

Clonidine has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 65,644 Clonidine users. Check the latest studies of Clonidine.

On Jul, 26, 2026

81 people who take Zyvox and Clonidine together, and have interactions are studied.

What are the common drug interactions of Zyvox and Clonidine, by gender? *:

female:

Diarrhoea haemorrhagic (bloody diarrhoea)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Haematoma (collection of blood outside the blood vessels)
Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)
Septic shock (shock due to blood infection)
Tooth abscess (pus formation in tooth)
Anaemia (lack of blood)
Candiduria (candida in urine)
Cardiac arrest

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Joint contracture (a permanent shortening of a muscle or joint)
Joint range of motion decreased (disease of joint movement)
Joint stiffness
Oedema (fluid collection in tissue)
Oedema peripheral (superficial swelling)
Quadriparesis (muscle weakness affecting all four limbs)
Skin hypertrophy (skin cells enlarges)
Skin tightness

What are the common drug interactions of Zyvox and Clonidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Acinetobacter infection (infection by group of bacteria commonly found in soil and water)
Diarrhoea
Diarrhoea haemorrhagic (bloody diarrhoea)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Haematoma (collection of blood outside the blood vessels)
Pleural effusion (water on the lungs)
Pyrexia (fever)
Septic shock (shock due to blood infection)
Tooth abscess (pus formation in tooth)

10-19:

n/a

20-29:

Renal failure (kidney dysfunction)
Chronic kidney disease
Emotional distress
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Death
Decreased activity
Fear
Impaired work ability

30-39:

Bradycardia (abnormally slow heart action)
Cardiac arrest
Hypotension (abnormally low blood pressure)
Abdominal pain
Anaphylactic reaction (serious allergic reaction)
Circulatory collapse

40-49:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac disorder
Cardiac failure congestive
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Chronic kidney disease
Renal failure (kidney dysfunction)
Cardiac failure
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Dyspnoea (difficult or laboured respiration)
Joint swelling

50-59:

Oedema peripheral (superficial swelling)
Pain
Quadriparesis (muscle weakness affecting all four limbs)
Skin hypertrophy (skin cells enlarges)
Skin tightness
Chronic kidney disease
Myosclerosis (hardening of muscle tissue)
Renal failure (kidney dysfunction)
Induration (thickening of tissue)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

60+:

Hypotension (abnormally low blood pressure)
Confusional state
Candiduria (candida in urine)
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Hypoxia (low oxygen in tissues)
Multiple injuries
Renal failure acute (rapid kidney dysfunction)
Staphylococcal bacteraemia (a bacterial infection of blood)
Surgery

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 13.58%
Diabetes: 11 people, 13.58%
Infection: 10 people, 12.35%
Pain: 9 people, 11.11%
Hiv Infection: 7 people, 8.64%
Stress And Anxiety: 6 people, 7.41%
High Blood Cholesterol: 6 people, 7.41%
Cardiac Disorder: 6 people, 7.41%
Nuclear Magnetic Resonance Imaging Brain: 5 people, 6.17%
Depression: 5 people, 6.17%

* Approximation only. Some reports may have incomplete information.

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