Zyvox and Diprivan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyvox (linezolid) and Diprivan (propofol). Common drug interactions include bone disorder among females and thrombocytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Zyvox and Diprivan. It is created by eHealthMe based on reports of 66 people who take the same drugs from the FDA, and is updated regularly.

What is Zyvox?

Zyvox has active ingredients of linezolid. It is often used in mrsa infection. eHealthMe is studying from 9,399 Zyvox users. Check the latest studies of Zyvox.

What is Diprivan?

Diprivan has active ingredients of propofol. eHealthMe is studying from 6,496 Diprivan users. Check the latest studies of Diprivan.



On Jul, 10, 2026

66 people who take Zyvox and Diprivan together, and have interactions are studied.

Zyvox and Diprivan drug interactions.

What are the common drug interactions of Zyvox and Diprivan, by gender? *:

female:

  1. Bone disorder
  2. Bone erosion
  3. Bone fragmentation
  4. Bone pain
  5. Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
  6. Colitis ulcerative (inflammation of colon with ulcer)
  7. Dental caries
  8. Diarrhoea
  9. Enteritis (inflammation of the small intestine)
  10. Enterococcal infection

male:

  1. Thrombocytopenia (decrease of platelets in blood)
  2. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  3. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  4. Drug ineffective
  5. Hypoacusis (loss of hearing)
  6. Leukopenia (less number of white blood cells in blood)
  7. Multi-organ failure (multisystem organ failure)
  8. Platelet count decreased
  9. Respiratory failure (inadequate gas exchange by the respiratory system)
  10. Septic shock (shock due to blood infection)

What are the common drug interactions of Zyvox and Diprivan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
  2. Hepatic steatosis (fatty liver disease)
  3. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  4. Blood catecholamines increased
  5. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  6. Epistaxis (bleed from the nose)
  7. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  8. Hepatic necrosis (large portions of liver die off due to severe liver disease)
  9. Hyperbilirubinaemia (excess of bilirubin in the blood)
  10. Hypersensitivity

20-29:

n/a

30-39:

  1. Femur fracture
  2. Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
  3. Tinea pedis (a contagious skin infection caused by the ringworm fungus)
  4. Chronic kidney disease
  5. Hyperkalaemia (damage to or disease of the kidney)
  6. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  7. Nephrogenic anaemia (anaemia due to kidney disease)
  8. Renal failure (kidney dysfunction)
  9. Renal injury (kidney injury)
  10. Renal ischaemia (lack of blood supply to kidney)

40-49:

n/a

50-59:

  1. Humerus fracture (injury to the upper arm bone)
  2. Joint dislocation (a joint position is changed from normal position)
  3. Lung disorder (lung disease)
  4. Malocclusion (a misalignment)
  5. Metastatic neoplasm (spreadable cancer tumour)
  6. Oedema peripheral (superficial swelling)
  7. Oliguria (not enough urine)
  8. Osteitis (a general term for inflammation of bone)
  9. Osteitis deformans (a disease of bone occurring in the middle aged and elderly; excessive bone destruction sometimes leading to bone pain)
  10. Osteoarthritis (a joint disease caused by cartilage loss in a joint)

60+:

  1. Sepsis (a severe blood infection that can lead to organ failure and death)
  2. Thrombocytopenia (decrease of platelets in blood)
  3. Blood creatinine increased
  4. Blood follicle stimulating hormone decreased
  5. Blood luteinising hormone decreased
  6. Blood testosterone increased
  7. Cardiac arrest
  8. Chills (felling of cold)
  9. Disease progression
  10. Disseminated intravascular coagulation (systemic activation of blood coagulation)

What are the existing conditions these people have? *

  1. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 27 people, 40.91%
  2. Osteoporosis (bones weak and more likely to break): 27 people, 40.91%
  3. Sepsis (a severe blood infection that can lead to organ failure and death): 12 people, 18.18%
  4. Thrombocytopenia (decrease of platelets in blood): 11 people, 16.67%
  5. Staphylococcal Infection (an infection with staphylococcus bacteria): 7 people, 10.61%
  6. Sedation: 7 people, 10.61%
  7. Sputum Abnormal: 4 people, 6.06%
  8. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs): 4 people, 6.06%

* Approximation only. Some reports may have incomplete information.

Do you take Zyvox and Diprivan?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zyvox and Diprivan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zyvox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Diprivan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zyvox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Diprivan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on linezolid and propofol (the active ingredients of Zyvox and Diprivan, respectively), and Zyvox and Diprivan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: