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A study for a 75 year old woman who takes Losartan, Indapamide, Amiloride Hydrochloride, Metformin Hydrochloride, Bisoprolol Fumarate (an AI-powered real world drug study)

Summary:

5 females aged 75 (±5) who take the same drugs and have adverse effects are studied. This is a phase IV clinical study for a 75 year old female patient who has High Blood Pressure, Asthma, Diabetes, Palpitations. The study is created by eHealthMe based on reports from sources including the FDA.

On Aug, 02, 2026

5 females aged 75 (±5) who take Losartan, Indapamide, Amiloride Hydrochloride, Metformin Hydrochloride, Bisoprolol Fumarate and have adverse effects are studied.

Number of reports submitted per year:

Losartan, Indapamide, Amiloride Hydrochloride, Metformin Hydrochloride, Bisoprolol Fumarate for a 75-year old woman.

Information of the patient in this study:

  • Age: 75
  • Gender: female

What are the drugs?

What are the conditions?

What are the adverse effects?

Comparison with patient's specific adverse outcomes:

You can check what is more associated with an adverse outcome: a drug mix, a drug, a condition, or a population of certain gender and age. Each patient is different. It is not uncommon that the results can be inconclusive or insignificant.

By the same drug(s):

  • Cough Aggravated:
    - among females aged 75 (±5) who take the same drugs: 0% (0 of 5)
    - among people who take the same drugs, regardless of gender or age: 0% (0 of 28)

By each condition:

  • people who have Cough Aggravated with High Blood Pressure:
    - among females aged 75 (±5) who have High Blood Pressure: 2.7% (2,067 of 76,491)
    - among people who have High Blood Pressure, regardless of gender or age: 2.65% (16,068 of 605,312)
  • people who have Cough Aggravated with Asthma:
    - among females aged 75 (±5) who have Asthma: 13.56% (2,489 of 18,354)
    - among people who have Asthma, regardless of gender or age: 10.33% (28,759 of 278,476)
  • people who have Cough Aggravated with Diabetes:
    - among females aged 75 (±5) who have Diabetes: 1.77% (506 of 28,552)
    - among people who have Diabetes, regardless of gender or age: 1.24% (4,545 of 367,724)
  • people who have Cough Aggravated with Palpitations:
    - among females aged 75 (±5) who have Palpitations: 3.33% (17 of 511)
    - among people who have Palpitations, regardless of gender or age: 4.52% (169 of 3,742)

By each drug (FDA data only):

  • people who take Losartan and have Cough Aggravated:
    - among females aged 75 (±5) who take Losartan and have side effects: 4.04% (864 of 21,405)
    - among people who take Losartan and have side effects, regardless of gender or age: 3.54% (6,049 of 170,800)
  • people who take Indapamide and have Cough Aggravated:
    - among females aged 75 (±5) who take Indapamide and have side effects: 3.63% (118 of 3,251)
    - among people who take Indapamide and have side effects, regardless of gender or age: 3.97% (859 of 21,642)
  • people who take Amiloride Hydrochloride and have Cough Aggravated:
    - among females aged 75 (±5) who take Amiloride Hydrochloride and have side effects: 7.69% (5 of 65)
    - among people who take Amiloride Hydrochloride and have side effects, regardless of gender or age: 2.41% (12 of 497)
  • people who take Metformin Hydrochloride and have Cough Aggravated:
    - among females aged 75 (±5) who take Metformin Hydrochloride and have side effects: 1.88% (94 of 5,008)
    - among people who take Metformin Hydrochloride and have side effects, regardless of gender or age: 2.62% (1,433 of 54,793)
  • people who take Bisoprolol Fumarate and have Cough Aggravated:
    - among females aged 75 (±5) who take Bisoprolol Fumarate and have side effects: 2.06% (106 of 5,140)
    - among people who take Bisoprolol Fumarate and have side effects, regardless of gender or age: 2.61% (1,017 of 39,020)

Common drug interactions *:

  1. Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 3 people, 60.00%
  2. Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 2 people, 40.00%
  3. Throat Tightness : 1 person, 20.00%
  4. Swollen Tongue (swelling of tongue): 1 person, 20.00%
  5. Nausea (feeling of having an urge to vomit): 1 person, 20.00%
  6. Hypersensitivity : 1 person, 20.00%
  7. Dizziness : 1 person, 20.00%
  8. Bile Duct Obstruction (blockage in the tubes that carry bile from the liver to the gallbladder): 1 person, 20.00%

Common co-existing conditions *:

You may use this to check any potential undetected conditions.

  1. Ovarian Cancer (cancer of ovary): 3 people, 60.00%

Common co-used drugs *:

You may use this to check any potential interacting drugs.

  1. Mirtazapine (3 people, 60.00%)
  2. Apixaban (3 people, 60.00%)
  3. Simvastatin (3 people, 60.00%)
  4. Pyridoxine (3 people, 60.00%)
  5. Prochlorperazine (3 people, 60.00%)
  6. Pantoprazole (3 people, 60.00%)
  7. Ondansetron (3 people, 60.00%)
  8. Tramadol (3 people, 60.00%)
  9. Magnesium Oxide (3 people, 60.00%)
  10. Lenvatinib (3 people, 60.00%)
  11. Hydrochlorothiazide (3 people, 60.00%)
  12. Oxycodone Hydrochloride (2 people, 40.00%)
  13. Gabapentin (1 person, 20.00%)
  14. Aspirin (1 person, 20.00%)
  15. Dapagliflozin (1 person, 20.00%)
  16. Fluticasone Propionate (1 person, 20.00%)
  17. Vitamins (1 person, 20.00%)
  18. Gliclazide (1 person, 20.00%)
  19. Oxycodone (1 person, 20.00%)
  20. Rosuvastatin Calcium (1 person, 20.00%)

Drug effectiveness *:

Losartan:

n/a

Indapamide:

n/a

Amiloride Hydrochloride:

n/a

Metformin Hydrochloride:

n/a

Bisoprolol Fumarate:

n/a

* Some reports may have incomplete information.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

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How the phase IV clinical study uses the data?

The study is based on gender, age, active ingredients of any drugs used. Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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