A study for a 53 year old woman who takes Lansoprazole, Esomeprazole Sodium, Fluoxetine (an AI-powered real world drug study)
Summary:
1,476 females aged 53 (±5) who take the same drugs and have adverse effects are studied. This is a phase IV clinical study for a 53 year old female patient who has Gerd, Gad. The study is created by eHealthMe based on reports from sources including the FDA.
1,476 females aged 53 (±5) who take Lansoprazole, Esomeprazole Sodium, Fluoxetine and have adverse effects are studied.
Number of reports submitted per year:

Information of the patient in this study:
- Age: 53
- Gender: female
What are the drugs?
- Lansoprazole has active ingredients of lansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 129,663 Lansoprazole users. Check the latest studies of Lansoprazole.
- Esomeprazole sodium has active ingredients of esomeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 3,583 Esomeprazole sodium users. Check the latest studies of Esomeprazole sodium.
- Fluoxetine has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 98,824 Fluoxetine users. Check the latest studies of Fluoxetine.
What are the conditions?
- Gerd (gastro-oesophageal reflux disease) is found to be associated with 3,033 drugs and 3,466 conditions by eHealthMe. Check the latest studies of Gerd.
- Gad is found to be associated with 777 drugs and 1,490 conditions by eHealthMe. Check the latest studies of Gad.
What are the adverse effects?
- Mouth ulceration (mouth ulcers) is found to be associated with 2,106 drugs and 2,206 conditions by eHealthMe. Check the latest studies of Mouth ulceration.
Comparison with patient's specific adverse outcomes:
You can check what is more associated with an adverse outcome: a drug mix, a drug, a condition, or a population of certain gender and age. Each patient is different. It is not uncommon that the results can be inconclusive or insignificant.
By the same drug(s):
-
Mouth Ulceration (mouth ulcers):
- among females aged 53 (±5) who take the same drugs: 0.07% (1 of 1,476)
- among people who take the same drugs, regardless of gender or age: 0.01% (1 of 14,143)
By each condition:
-
people who have Mouth Ulceration with Gerd:
- among females aged 53 (±5) who have Gerd: 0.08% (25 of 32,119)
- among people who have Gerd, regardless of gender or age: 0.08% (251 of 328,777) -
people who have Mouth Ulceration with Gad:
- among females aged 53 (±5) who have Gad: 0.08% (1 of 1,261)
- among people who have Gad, regardless of gender or age: 0.1% (14 of 13,638)
By each drug (FDA data only):
-
people who take Lansoprazole and have Mouth Ulceration:
- among females aged 53 (±5) who take Lansoprazole and have side effects: 0.53% (48 of 9,023)
- among people who take Lansoprazole and have side effects, regardless of gender or age: 0.45% (581 of 128,099) -
people who take Esomeprazole Sodium and have Mouth Ulceration:
- among females aged 53 (±5) who take Esomeprazole Sodium and have side effects: 0% (0 of 391)
- among people who take Esomeprazole Sodium and have side effects, regardless of gender or age: 0.23% (8 of 3,503) -
people who take Fluoxetine and have Mouth Ulceration:
- among females aged 53 (±5) who take Fluoxetine and have side effects: 0.26% (28 of 10,970)
- among people who take Fluoxetine and have side effects, regardless of gender or age: 0.16% (154 of 94,397)
Common drug interactions *:
- Chronic Kidney Disease : 512 people, 34.69%
- Acute Kidney Failure : 256 people, 17.34%
- Nausea (feeling of having an urge to vomit): 163 people, 11.04%
- Pain : 142 people, 9.62%
- Fatigue (feeling of tiredness): 142 people, 9.62%
- Weakness : 139 people, 9.42%
- Joint Pain : 122 people, 8.27%
- Dizziness : 121 people, 8.20%
- Renal Injury (kidney injury): 117 people, 7.93%
- Dyspnea (difficult or laboured breathing): 111 people, 7.52%
- Drug Ineffective : 105 people, 7.11%
- Abdominal Pain Upper : 99 people, 6.71%
- Diarrhea : 97 people, 6.57%
- Cough : 96 people, 6.50%
- Hyperhidrosis (abnormally increased sweating): 94 people, 6.37%
- Fall : 87 people, 5.89%
- Back Pain : 86 people, 5.83%
- Hypotension (abnormally low blood pressure): 85 people, 5.76%
- Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 80 people, 5.42%
- Dry Mouth : 80 people, 5.42%
Common co-existing conditions *:
You may use this to check any potential undetected conditions.
- Pain : 301 people, 20.39%
- High Blood Pressure : 282 people, 19.11%
- High Blood Cholesterol : 217 people, 14.70%
- Infection : 141 people, 9.55%
- Diabetes : 95 people, 6.44%
- Indigestion : 80 people, 5.42%
- Blood Pressure Abnormal : 80 people, 5.42%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 72 people, 4.88%
- Nausea (feeling of having an urge to vomit): 59 people, 4.00%
- Multiple Allergies (allergy to multiple agents): 57 people, 3.86%
- Asthma : 56 people, 3.79%
- Hypersensitivity : 55 people, 3.73%
- Cardiac Disorder : 48 people, 3.25%
- Insomnia (sleeplessness): 48 people, 3.25%
- Neuralgia (pain in one or more nerves): 47 people, 3.18%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 45 people, 3.05%
- Migraine (headache): 43 people, 2.91%
- Headache (pain in head): 37 people, 2.51%
- Sleep Disorder : 36 people, 2.44%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 36 people, 2.44%
Common co-used drugs *:
You may use this to check any potential interacting drugs.
- Nexium (568 people, 38.48%)
- Prilosec (503 people, 34.08%)
- Protonix (463 people, 31.37%)
- Nexium 24hr (368 people, 24.93%)
- Pantoprazole (353 people, 23.92%)
- Prilosec Otc (312 people, 21.14%)
- Dexilant (189 people, 12.80%)
- Cymbalta (149 people, 10.09%)
- Aspirin (142 people, 9.62%)
- Amlodipine (119 people, 8.06%)
- Zantac (113 people, 7.66%)
- Enbrel (112 people, 7.59%)
- Pepcid (111 people, 7.52%)
- Lipitor (110 people, 7.45%)
- Benadryl (104 people, 7.05%)
- Metformin (103 people, 6.98%)
- Omeprazole (103 people, 6.98%)
- Prednisone (95 people, 6.44%)
- Lyrica (91 people, 6.17%)
- Ambien (88 people, 5.96%)
Drug effectiveness *:
Lansoprazole:
- not at all: 0 %
- somewhat: 50 %
- moderate: 50 %
- high: 0 %
- very high: 0 %
Esomeprazole Sodium:
n/a
Fluoxetine:
- not at all: 0 %
- somewhat: 0 %
- moderate: 50 %
- high: 50 %
- very high: 0 %
* Some reports may have incomplete information.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related studies
Drug side effects in long term, by gender and age:
- Esomeprazole sodium: 3,583 reports
- Fluoxetine: 98,824 reports
- Lansoprazole: 129,663 reports
Treatments, associated medications and conditions:
- Gad: 31,282 reports
- Gerd: 445,836 reports
- Mouth ulceration: 28,861 reports
Drug side effects:
- Lansoprazole and Mouth ulceration (581 reports)
- Esomeprazole sodium and Mouth ulceration
- Fluoxetine and Mouth ulceration (154 reports)
Drug interactions:
- Lansoprazole and Esomeprazole sodium drug interaction (84 reports)
- Lansoprazole and Fluoxetine drug interaction (2,780 reports)
- Esomeprazole sodium and Fluoxetine drug interaction (27 reports)
Symptoms:
- Gerd and Mouth ulceration (251 reports)
- Gad and Mouth ulceration (14 reports)
Drugs that are associated with:
- Mouth ulceration: 2,106 drugs
Conditions that are associated with:
- Mouth ulceration: 2,206 conditions
How the phase IV clinical study uses the data?
The study is based on gender, age, active ingredients of any drugs used. Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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