1. Home
  2. Analysis
  3. Methotrexate-preservative-free

Methotrexate preservative free side effects, by duration, gender and age (a phase IV clinical study of FDA data)

Summary:

Side effects are reported by people who take Methotrexate preservative free (methotrexate sodium). Common side effects include arthralgia among females and abasia among males.

The phase IV clinical study is created by eHealthMe based on 7 reports from the FDA, and is updated regularly.

What is Methotrexate Preservative Free?

Methotrexate preservative free has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. eHealthMe is studying from 160 Methotrexate preservative free users. Check the latest studies of Methotrexate preservative free.

On Jul, 07, 2026

7 people who take Methotrexate Preservative Free and have side effects are studied.

Methotrexate preservative free side effects.

What are the common side effects of Methotrexate Preservative Free, by gender? *:

female:

  1. Arthralgia (joint pain)

male:

  1. Abasia (inability to walk)
  2. Abnormal behaviour
  3. Prostate cancer

What are the common side effects of Methotrexate Preservative Free, by age (0-1 to 60+) *:

0-1:

n/a

2-9:

  1. Abasia (inability to walk)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Arthralgia (joint pain)
  2. Prostate cancer

What are the common side effects of Methotrexate Preservative Free, by the time people have been on the drug (< 1 month to 10+ years)? *:

< 1 month:

n/a

1 - 6 months:

  1. Abnormal behaviour

6 - 12 months:

n/a

1 - 2 years:

n/a

2 - 5 years:

n/a

5 - 10 years:

n/a

10+ years:

  1. Arthralgia (joint pain)

not specified:

  1. Abasia (inability to walk)
  2. Prostate cancer

* Approximation only. Some reports may have incomplete information.

Do you take Methotrexate preservative free?

- Personalize this study to your gender and age
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related publications that referenced our studies

How the study uses the data?

The study is based on methotrexate sodium (the active ingredients of Methotrexate preservative free) and Methotrexate preservative free (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.

Related studies are listed below in case you need more information:

Alternative drugs to, pros and cons of Methotrexate preservative free:

All Methotrexate preservative free side effects from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.