Sodium succinate side effects, by duration, gender and age (a phase IV clinical study of FDA data)

female:

1. Abdominal pain
2. Fatigue (feeling of tiredness)
3. Abdominal discomfort
4. Abdominal mass (localized enlargement or swelling in the human abdomen)
5. Asthenia (weakness)
6. Bladder irritation
7. Diarrhoea
8. Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
9. Abdominal distension
10. Adult t-cell lymphoma/leukaemia (cancer of the immune system's own t-cells)

male:

1. Acute respiratory failure
2. Cardiac failure
3. Blood pressure decreased
4. Cerebral haemorrhage (bleeding within the brain)
5. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
6. Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
7. Device dislocation
8. Drug ineffective
9. Erythema multiforme (a type of hypersensitivity reaction)
10. Fall

0-1:

1. Anaemia postoperative

2-9:

1. Alanine aminotransferase increased

10-19:

1. Blood smear test abnormal
2. Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
3. Fatigue (feeling of tiredness)

20-29:

1. Aphthous stomatitis (mouth ulcer)

30-39:

1. Calciphylaxis (is a syndrome with vascular calcium accumulation)
2. Anaphylactic reaction (serious allergic reaction)
3. Erythema multiforme (a type of hypersensitivity reaction)

40-49:

1. Abdominal pain
2. Abdominal mass (localized enlargement or swelling in the human abdomen)
3. Abdominal distension
4. Anaemia (lack of blood)
5. Asthenia (weakness)
6. Cerebral haemorrhage (bleeding within the brain)
7. Cytomegalovirus chorioretinitis (infection of choroid and retina of the eye from virus)
8. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
9. Hypoventilation (too shallow or too slow breathing, which does not meet the needs of the body)
10. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)

50-59:

1. Abdominal discomfort
2. Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
3. Abdominal distension
4. Arthralgia (joint pain)
5. Back pain
6. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
7. Drug ineffective
8. Fall
9. Purpura (purplish discoloration of the skin)

60+:

1. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
2. Diarrhoea
3. Acute respiratory distress syndrome
4. Adult t-cell lymphoma/leukaemia (cancer of the immune system's own t-cells)
5. Adverse drug reaction
6. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
7. Anaphylactic reaction (serious allergic reaction)
8. Blood pressure decreased
9. Blood pressure systolic abnormal
10. Cellulitis (infection under the skin)

< 1 month:

1. Cardiac failure
2. Alanine aminotransferase increased
3. Anaemia (lack of blood)
4. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
5. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

1 - 6 months:

n/a

6 - 12 months:

n/a

1 - 2 years:

n/a

2 - 5 years:

n/a

5 - 10 years:

n/a

10+ years:

n/a

not specified:

1. Abdominal mass (localized enlargement or swelling in the human abdomen)
2. Anaphylactic reaction (serious allergic reaction)
3. Asthenia (weakness)
4. Bladder irritation
5. Calciphylaxis (is a syndrome with vascular calcium accumulation)
6. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
7. Diarrhoea
8. Drug ineffective
9. Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
10. Acute respiratory distress syndrome