Abilify and Hyperphagia - a phase IV clinical study of FDA data

Summary:

Hyperphagia is reported as a side effect among people who take Abilify (aripiprazole), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Amisulpride, and have Schizophrenia.

The phase IV clinical study analyzes which people have Hyperphagia when taking Abilify. It is created by eHealthMe based on reports of 97,308 people who have side effects when taking Abilify from the FDA, and is updated regularly.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,441 Abilify users. Check the latest studies of Abilify.

What is Hyperphagia?

Hyperphagia (an abnormal appetite for food) is found to be associated with 2,306 drugs and 1,931 conditions by eHealthMe. Check the latest studies of Hyperphagia.



On Aug, 14, 2025

97,308 people reported to have side effects when taking Abilify.
Among them, 1,087 people (1.12%) have Hyperphagia.

Could Abilify cause Hyperphagia?

Among these 1,087 people:

How long have people been on Abilify when they have Hyperphagia? *

  • < 1 month: 24.66 %
  • 1 - 6 months: 29.45 %
  • 6 - 12 months: 5.48 %
  • 1 - 2 years: 6.85 %
  • 2 - 5 years: 14.38 %
  • 5 - 10 years: 16.44 %
  • 10+ years: 2.74 %

What is the gender of people who have Hyperphagia when taking Abilify? *

  • female: 52.03 %
  • male: 47.97 %

What is the age of people who have Hyperphagia when taking Abilify? *

  • 0-1: 0.0 %
  • 2-9: 4.92 %
  • 10-19: 11.54 %
  • 20-29: 16.46 %
  • 30-39: 12.46 %
  • 40-49: 26.77 %
  • 50-59: 14.62 %
  • 60+: 13.23 %

What are other drugs people take besides Abilify? *

  1. Amisulpride: 148 people, 13.62%
  2. Saphris: 134 people, 12.33%
  3. Asenapine Maleate: 110 people, 10.12%
  4. Fluoxetine: 109 people, 10.03%
  5. Risperdal: 102 people, 9.38%
  6. Seroquel: 101 people, 9.29%
  7. Zyprexa: 93 people, 8.56%
  8. Lithium Carbonate: 89 people, 8.19%
  9. Gabapentin: 85 people, 7.82%
  10. Lamictal: 82 people, 7.54%

What are other side effects people have besides Hyperphagia? *

  1. Weight Increased: 697 people, 64.12%
  2. Fatigue (feeling of tiredness): 209 people, 19.23%
  3. Drug Ineffective: 207 people, 19.04%
  4. Akathisia (a movement disorder characterized by a feeling of inner restlessness): 190 people, 17.48%
  5. Suicide Attempt: 189 people, 17.39%
  6. Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 187 people, 17.20%
  7. High Blood Pressure: 184 people, 16.93%
  8. Drowsiness: 166 people, 15.27%
  9. Weight Loss: 160 people, 14.72%
  10. Euphoric Mood (excessively happy but may become angry or irritable): 153 people, 14.08%

What are the existing conditions these people have? *

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 257 people, 23.64%
  2. Psychotic Disorder: 154 people, 14.17%
  3. Affective Disorder (mental disorder): 122 people, 11.22%
  4. Stress And Anxiety: 104 people, 9.57%
  5. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 63 people, 5.80%
  6. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 51 people, 4.69%
  7. Sleep Disorder: 42 people, 3.86%
  8. Insomnia (sleeplessness): 37 people, 3.40%
  9. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 37 people, 3.40%
  10. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 34 people, 3.13%

* Approximation only. Some reports may have incomplete information.

Do you take Abilify and have Hyperphagia?

- Check whether Hyperphagia is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Abilify:

Hyperphagia treatments and more:

How severe was Hyperphagia and when was it recovered:

Expand to all the drugs that have ingredients of aripiprazole:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Abilify side effects:

Browse all side effects of Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Hyperphagia:

Browse all the drugs that are associated with Hyperphagia:

Common conditions associated with Hyperphagia:

Browse all the conditions that are associated with Hyperphagia:

Drugs similar to Abilify and Hyperphagia :

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on aripiprazole (the active ingredients of Abilify) and Abilify (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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