Abilify and Left ventricular dysfunction - a phase IV clinical study of FDA data

Summary:

Left ventricular dysfunction is reported as a side effect among people who take Abilify (aripiprazole), especially for people who are female, 40-49 old, have been taking the drug for 5 - 10 years also take Cymbalta, and have Bipolar ii disorder.

The phase IV clinical study analyzes which people have Left ventricular dysfunction when taking Abilify. It is created by eHealthMe based on reports of 97,308 people who have side effects when taking Abilify from the FDA, and is updated regularly.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,441 Abilify users. Check the latest studies of Abilify.

What is Left ventricular dysfunction?

Left ventricular dysfunction is found to be associated with 951 drugs and 784 conditions by eHealthMe. Check the latest studies of Left ventricular dysfunction.



On Aug, 22, 2025

97,308 people reported to have side effects when taking Abilify.
Among them, 58 people (0.06%) have Left ventricular dysfunction.

Could Abilify cause Left ventricular dysfunction?

Among these 58 people:

How long have people been on Abilify when they have Left ventricular dysfunction? *

  • < 1 month: 20 %
  • 1 - 6 months: 40 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 40 %
  • 10+ years: 0.0 %

What is the gender of people who have Left ventricular dysfunction when taking Abilify? *

  • female: 82.14 %
  • male: 17.86 %

What is the age of people who have Left ventricular dysfunction when taking Abilify? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 1.92 %
  • 30-39: 3.85 %
  • 40-49: 59.62 %
  • 50-59: 23.08 %
  • 60+: 11.54 %

What are other drugs people take besides Abilify? *

  1. Cymbalta: 37 people, 63.79%
  2. Prozac: 35 people, 60.34%
  3. Concerta: 34 people, 58.62%
  4. Asacol: 32 people, 55.17%
  5. Topamax: 14 people, 24.14%
  6. Crestor: 9 people, 15.52%
  7. Lorazepam: 8 people, 13.79%
  8. Coumadin: 8 people, 13.79%
  9. Vicodin: 8 people, 13.79%
  10. Celexa: 8 people, 13.79%

What are other side effects people have besides Left ventricular dysfunction? *

  1. Cardiac Arrest: 35 people, 60.34%
  2. Hypoxic-Ischaemic Encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total): 34 people, 58.62%
  3. Pneumonia: 30 people, 51.72%
  4. Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 24 people, 41.38%
  5. Blood Glucose Increased: 16 people, 27.59%
  6. Blood Bicarbonate Decreased: 13 people, 22.41%
  7. Hypokalemia (low potassium): 13 people, 22.41%
  8. Dyspnea (difficult or laboured breathing): 12 people, 20.69%
  9. High Blood Cholesterol: 10 people, 17.24%
  10. Dizziness: 10 people, 17.24%

What are the existing conditions these people have? *

  1. Bipolar Ii Disorder (characterized by at least one episode of hypomania and at least one episode of major depression): 32 people, 55.17%
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints): 7 people, 12.07%
  3. Metastases To Bone (cancer spreads to bone): 7 people, 12.07%
  4. Stress And Anxiety: 4 people, 6.90%
  5. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 4 people, 6.90%
  6. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 2 people, 3.45%
  7. Infection: 2 people, 3.45%
  8. Cardiac Failure: 1 person, 1.72%
  9. Aspergillosis (an infection caused by a fungus called aspergillus): 1 person, 1.72%
  10. Asteatosis (any disease that persistently causes the skin to dry): 1 person, 1.72%

* Approximation only. Some reports may have incomplete information.

Do you take Abilify and have Left ventricular dysfunction?

- Check whether Left ventricular dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Abilify:

Left ventricular dysfunction treatments and more:

How severe was Left ventricular dysfunction and when was it recovered:

Expand to all the drugs that have ingredients of aripiprazole:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Left ventricular dysfunction:

Browse all the conditions that are associated with Left ventricular dysfunction:

Drugs similar to Abilify and Left ventricular dysfunction :

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on aripiprazole (the active ingredients of Abilify) and Abilify (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: