Abraxane and Hepatomegaly - a phase IV clinical study of FDA data
Summary:
Hepatomegaly is reported as a side effect among people who take Abraxane (paclitaxel), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Avastin, and have Metastases to bone.
The phase IV clinical study analyzes which people have Hepatomegaly when taking Abraxane. It is created by eHealthMe based on reports of 19,123 people who have side effects when taking Abraxane from the FDA, and is updated regularly.
What is Abraxane?
Abraxane has active ingredients of paclitaxel. It is often used in breast cancer metastatic. eHealthMe is studying from 19,196 Abraxane users. Check the latest studies of Abraxane.
What is Hepatomegaly?
Hepatomegaly (abnormal enlargement of the liver) is found to be associated with 1,314 drugs and 1,924 conditions by eHealthMe. Check the latest studies of Hepatomegaly.
19,123 people reported to have side effects when taking Abraxane.
Among them, 38 people (0.2%) have Hepatomegaly.

Among these 38 people:
How long have people been on Abraxane when they have Hepatomegaly? *
- < 1 month: 50 %
- 1 - 6 months: 25 %
- 6 - 12 months: 25 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Hepatomegaly when taking Abraxane? *
- female: 92.11 %
- male: 7.89 %
What is the age of people who have Hepatomegaly when taking Abraxane? *
- 0-1: 0.0 %
- 2-9: 5.88 %
- 10-19: 2.94 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 35.29 %
- 50-59: 41.18 %
- 60+: 14.71 %
What are other drugs people take besides Abraxane? *
- Avastin: 21 people, 55.26%
- Zometa: 20 people, 52.63%
- Aredia: 17 people, 44.74%
- Lexapro: 14 people, 36.84%
- Flagyl: 11 people, 28.95%
- Faslodex: 11 people, 28.95%
- Neurontin: 10 people, 26.32%
- Navelbine: 10 people, 26.32%
- Lyrica: 10 people, 26.32%
- Synthroid: 10 people, 26.32%
What are other side effects people have besides Hepatomegaly? *
- Pneumonia: 20 people, 52.63%
- Metastases To Bone (cancer spreads to bone): 19 people, 50.00%
- Back Pain: 19 people, 50.00%
- Nausea (feeling of having an urge to vomit): 18 people, 47.37%
- Diarrhea: 18 people, 47.37%
- Pain: 17 people, 44.74%
- Osteonecrosis Of Jaw (death of bone of jaw): 17 people, 44.74%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 17 people, 44.74%
- Stress And Anxiety: 17 people, 44.74%
- Fever: 15 people, 39.47%
What are the existing conditions these people have? *
- Metastases To Bone (cancer spreads to bone): 9 people, 23.68%
- Pain: 8 people, 21.05%
- Depression: 7 people, 18.42%
- Breast Cancer Female: 5 people, 13.16%
- Bone Loss: 3 people, 7.89%
- Osteoporosis (bones weak and more likely to break): 3 people, 7.89%
- Metastases To Liver (cancer spreads to liver): 2 people, 5.26%
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 2 people, 5.26%
- Metastases To Bone Marrow (cancer spreads to bone marrow): 2 people, 5.26%
- Metastases To Lung (cancer spreads to lung): 2 people, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Abraxane and have Hepatomegaly?
- Check whether Hepatomegaly is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Abraxane:
- Abraxane (19,196 reports)
Hepatomegaly treatments and more:
- Hepatomegaly (20,071 reports)
How severe was Hepatomegaly and when was it recovered:
Expand to all the drugs that have ingredients of paclitaxel:
- Hepatomegaly and drugs with ingredients of paclitaxel (150 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Abraxane:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Hepatomegaly:
- Hepatomegaly (1,314 drugs)
Browse all the conditions that are associated with Hepatomegaly:
- Hepatomegaly (1,924 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on paclitaxel (the active ingredients of Abraxane) and Abraxane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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