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Accutane and Thyroid function test abnormal - a phase IV clinical study of FDA data

Summary:

Thyroid function test abnormal is reported as a side effect among people who take Accutane (isotretinoin), especially for people who are female, 30-39 old, have been taking the drug for 1 - 6 months also take Synthroid, and have Hypothyroidism.

The phase IV clinical study analyzes which people have Thyroid function test abnormal when taking Accutane. It is created by eHealthMe based on reports of 33,410 people who have side effects when taking Accutane from the FDA, and is updated regularly.

What is Accutane?

Accutane has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 35,221 Accutane users. Check the latest studies of Accutane.

What is Thyroid function test abnormal?

Thyroid function test abnormal is found to be associated with 1,667 drugs and 1,587 conditions by eHealthMe. Check the latest studies of Thyroid function test abnormal.

On Jan, 21, 2026

33,410 people reported to have side effects when taking Accutane.
Among them, 41 people (0.12%) have Thyroid function test abnormal.

Could Accutane cause Thyroid function test abnormal?

Among these 41 people:

How long have people been on Accutane when they have Thyroid function test abnormal? *

  • < 1 month: 11.11 %
  • 1 - 6 months: 55.56 %
  • 6 - 12 months: 2.78 %
  • 1 - 2 years: 16.67 %
  • 2 - 5 years: 5.56 %
  • 5 - 10 years: 5.56 %
  • 10+ years: 2.78 %

What is the gender of people who have Thyroid function test abnormal when taking Accutane? *

  • female: 90 %
  • male: 10 %

What is the age of people who have Thyroid function test abnormal when taking Accutane? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 16.67 %
  • 20-29: 22.22 %
  • 30-39: 36.11 %
  • 40-49: 8.33 %
  • 50-59: 2.78 %
  • 60+: 13.89 %

What are other drugs people take besides Accutane? *

  1. Synthroid: 10 people, 24.39%
  2. Minoxidil: 5 people, 12.20%
  3. Erythromycin: 4 people, 9.76%
  4. Cleocin T: 4 people, 9.76%
  5. Retin-A: 3 people, 7.32%
  6. Ibuprofen: 3 people, 7.32%
  7. Minocin: 3 people, 7.32%
  8. Benzamycin: 3 people, 7.32%
  9. Benzaclin: 3 people, 7.32%
  10. Amnesteem: 3 people, 7.32%

What are other side effects people have besides Thyroid function test abnormal? *

  1. Inflammatory Bowel Disease: 26 people, 63.41%
  2. Depression: 23 people, 56.10%
  3. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 20 people, 48.78%
  4. Headache (pain in head): 19 people, 46.34%
  5. Vision Blurred: 17 people, 41.46%
  6. Muscle Aches (muscle pain): 16 people, 39.02%
  7. Insomnia (sleeplessness): 15 people, 36.59%
  8. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 15 people, 36.59%
  9. Rashes (redness): 15 people, 36.59%
  10. Nausea (feeling of having an urge to vomit): 15 people, 36.59%

What are the existing conditions these people have? *

  1. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 19.51%
  2. Irritable Bowel Syndrome: 2 people, 4.88%
  3. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 2 people, 4.88%
  4. Pain: 2 people, 4.88%
  5. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 4.88%
  6. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 4.88%
  7. Multiple Myeloma (cancer of the plasma cells): 2 people, 4.88%
  8. Laryngitis (inflammation of the larynx): 2 people, 4.88%
  9. Sinusitis (inflammation of sinus): 2 people, 4.88%
  10. High Blood Pressure: 2 people, 4.88%

* Approximation only. Some reports may have incomplete information.

Do you take Accutane and have Thyroid function test abnormal?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Accutane:

Thyroid function test abnormal treatments and more:

How severe was Thyroid function test abnormal and when was it recovered:

Expand to all the drugs that have ingredients of isotretinoin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Accutane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thyroid function test abnormal:

Browse all the conditions that are associated with Thyroid function test abnormal:

Drugs similar to Accutane and Thyroid function test abnormal :

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on isotretinoin (the active ingredients of Accutane) and Accutane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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